Csp3−H Activation without Chelation Assistance in an Iridium Pincer Complex Forming Cyclometallated Products

David A. Ahlstrand; Alexey V. Polukeev; Rocío Marcos; Mårten S G Ahlquist; Ola F. Wendt

doi:10.1002/chem.201604469

Csp³−H Activation without Chelation Assistance in an Iridium Pincer Complex Forming Cyclometallated Products

David A. Ahlstrand, Alexey V. Polukeev, Rocío Marcos, Mårten S G Ahlquist, Ola F. Wendt

Centre for Analysis and Synthesis

Research output: Contribution to journal › Article › peer-review

Abstract

Cyclometallation of 8-methylquinoline and 2-(dimethylamino)-pyridine in an iridium-based pincer complex is described. The C−H activation of 2-(dimethylamino)pyridine is not chelation assisted, which has not been described before for Csp³−H bonds in cyclometallation reactions. The mechanism of the cyclometallation of 2-(dimethylamino)pyridine was studied by DFT calculations and kinetic measurements.

Original language	English
Pages (from-to)	1748-1751
Number of pages	4
Journal	Chemistry - A European Journal
Volume	23
Issue number	8
DOIs	https://doi.org/10.1002/chem.201604469
Publication status	Published - 2017

Subject classification (UKÄ)

Analytical Chemistry

Free keywords

cyclometallation
density functional calculations
iridium
pincer complexes
undirected C−H activation

Access to Document

10.1002/chem.201604469

Cite this

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title = "Csp3−H Activation without Chelation Assistance in an Iridium Pincer Complex Forming Cyclometallated Products",

abstract = "Cyclometallation of 8-methylquinoline and 2-(dimethylamino)-pyridine in an iridium-based pincer complex is described. The C−H activation of 2-(dimethylamino)pyridine is not chelation assisted, which has not been described before for Csp3−H bonds in cyclometallation reactions. The mechanism of the cyclometallation of 2-(dimethylamino)pyridine was studied by DFT calculations and kinetic measurements.",

keywords = "cyclometallation, density functional calculations, iridium, pincer complexes, undirected C−H activation",

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year = "2017",

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T1 - Csp3−H Activation without Chelation Assistance in an Iridium Pincer Complex Forming Cyclometallated Products

AU - Ahlstrand, David A.

AU - Polukeev, Alexey V.

AU - Marcos, Rocío

AU - Ahlquist, Mårten S G

AU - Wendt, Ola F.

PY - 2017

Y1 - 2017

N2 - Cyclometallation of 8-methylquinoline and 2-(dimethylamino)-pyridine in an iridium-based pincer complex is described. The C−H activation of 2-(dimethylamino)pyridine is not chelation assisted, which has not been described before for Csp3−H bonds in cyclometallation reactions. The mechanism of the cyclometallation of 2-(dimethylamino)pyridine was studied by DFT calculations and kinetic measurements.

AB - Cyclometallation of 8-methylquinoline and 2-(dimethylamino)-pyridine in an iridium-based pincer complex is described. The C−H activation of 2-(dimethylamino)pyridine is not chelation assisted, which has not been described before for Csp3−H bonds in cyclometallation reactions. The mechanism of the cyclometallation of 2-(dimethylamino)pyridine was studied by DFT calculations and kinetic measurements.

KW - cyclometallation

KW - density functional calculations

KW - iridium

KW - pincer complexes

KW - undirected C−H activation

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