Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

A. Grubb

doi:10.1016/B978-0-12-803014-1.00005-4

Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

A. Grubb

Skåne University Hospital

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Abstract

Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."

Original language	English
Title of host publication	Biomarkers of Kidney Disease
Editors	C.L. Edelstein
Publisher	Elsevier
Pages	225-240
Number of pages	16
Edition	2
ISBN (Print)	9780128030141
DOIs	https://doi.org/10.1016/B978-0-12-803014-1.00005-4
Publication status	Published - 2017

Subject classification (UKÄ)

Clinical Laboratory Medicine

Free keywords

Biomarker
Creatinine
Cystatin C
GFR-estimating equations
Internal and external validation
Renal reserve
Shrunken Pore Syndrome

Access to Document

10.1016/B978-0-12-803014-1.00005-4

Cite this

@inbook{1c32d3041a344770836bebf87ecea8aa,

title = "Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining {"}Shrunken Pore Syndrome{"}",

abstract = "Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of {"}Biomarkers of Kidney Disease.{"} This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called {"}Shrunken Pore Syndrome.{"}",

keywords = "Biomarker, Creatinine, Cystatin C, GFR-estimating equations, Internal and external validation, Renal reserve, Shrunken Pore Syndrome",

author = "A. Grubb",

year = "2017",

doi = "10.1016/B978-0-12-803014-1.00005-4",

language = "English",

isbn = "9780128030141",

pages = "225--240",

editor = "C.L. Edelstein",

booktitle = "Biomarkers of Kidney Disease",

publisher = "Elsevier",

address = "United States",

edition = "2",

}

TY - CHAP

T1 - Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

AU - Grubb, A.

PY - 2017

Y1 - 2017

N2 - Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."

AB - Cystatin C, a basic nonglycosylated 13.3 kDa protein comprising a single polypeptide chain of 120 amino acid residues, is produced at a stable rate from a housekeeping gene in all nucleated cells and eliminated from the circulation by free filtration through the glomerular membranes as described in the first edition of "Biomarkers of Kidney Disease." This discourse will report some of the progress in the use of cystatin C as a multifaceted marker of kidney disease, which has occurred since then, including its role in identifying the novel syndrome called "Shrunken Pore Syndrome."

KW - Biomarker

KW - Creatinine

KW - Cystatin C

KW - GFR-estimating equations

KW - Internal and external validation

KW - Renal reserve

KW - Shrunken Pore Syndrome

UR - http://www.scopus.com/inward/record.url?scp=85010190522&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-803014-1.00005-4

DO - 10.1016/B978-0-12-803014-1.00005-4

M3 - Book chapter

SN - 9780128030141

SP - 225

EP - 240

BT - Biomarkers of Kidney Disease

A2 - Edelstein, C.L.

PB - Elsevier

ER -

Cystatin C as a Multifaceted Biomarker in Kidney Disease and Its Role in Defining "Shrunken Pore Syndrome"

Abstract

Subject classification (UKÄ)

Free keywords

Access to Document

Other files and links

Fingerprint

Cite this