Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.

Fredrik Sjövall; Saori Morota; Eleonor Åsander Frostner; Magnus Hansson; Eskil Elmer

doi:10.1371/journal.pone.0097673

Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.

Fredrik Sjövall, Saori Morota, Eleonor Åsander Frostner, Magnus Hansson, Eskil Elmer

Research output: Contribution to journal › Article › peer-review

174 Downloads (Pure)

Abstract

The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis. Therefore, we investigated the correlation between observed changes in platelet mitochondrial respiration and a set of pro- and anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.

Original language	English
Article number	e97673
Journal	PLoS ONE
Volume	9
Issue number	5
DOIs	https://doi.org/10.1371/journal.pone.0097673
Publication status	Published - 2014

Subject classification (UKÄ)

Cardiac and Cardiovascular Systems
Neurology
Respiratory Medicine and Allergy

Access to Document

10.1371/journal.pone.0097673

Plos_SjAPvall_et_al

http://www.ncbi.nlm.nih.gov/pubmed/24828117?dopt=Abstract

Cite this

@article{58a05b0fb30c4e9088611f9c135f9b09,

title = "Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.",

abstract = "The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis. Therefore, we investigated the correlation between observed changes in platelet mitochondrial respiration and a set of pro- and anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.",

author = "Fredrik Sj{\"o}vall and Saori Morota and {{\AA}sander Frostner}, Eleonor and Magnus Hansson and Eskil Elmer",

year = "2014",

doi = "10.1371/journal.pone.0097673",

language = "English",

volume = "9",

journal = "PLoS ONE",

issn = "1932-6203",

publisher = "Public Library of Science (PLoS)",

number = "5",

}

TY - JOUR

T1 - Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.

AU - Sjövall, Fredrik

AU - Morota, Saori

AU - Åsander Frostner, Eleonor

AU - Hansson, Magnus

AU - Elmer, Eskil

PY - 2014

Y1 - 2014

N2 - The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis. Therefore, we investigated the correlation between observed changes in platelet mitochondrial respiration and a set of pro- and anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.

AB - The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis. Therefore, we investigated the correlation between observed changes in platelet mitochondrial respiration and a set of pro- and anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.

U2 - 10.1371/journal.pone.0097673

DO - 10.1371/journal.pone.0097673

M3 - Article

C2 - 24828117

VL - 9

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 5

M1 - e97673

ER -

Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Cite this