Abstract
Decoding transcriptional effects of experimental tissue-tissue or cell-cell interactions is important; for example, to better understand tumor-stroma interactions after transplantation of human cells into mouse (xenografting). Transcriptome analysis of intermixed human and mouse cells has, however, frequently relied on the need to separate the two cell populations prior to transcriptome analysis, which introduces confounding effects on gene expression.
Original language | English |
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Article number | 109 |
Journal | Breast Cancer Research |
Volume | 17 |
DOIs | |
Publication status | Published - 2015 |
Subject classification (UKÄ)
- Cancer and Oncology