TY - JOUR
T1 - Decoding breast cancer tissue-stroma interactions using species-specific sequencing.
AU - Chivukula, Indira V
AU - Ramsköld, Daniel
AU - Storvall, Helena
AU - Anderberg, Charlotte
AU - Jin, Shaobo
AU - Mamaeva, Veronika
AU - Sahlgren, Cecilia
AU - Pietras, Kristian
AU - Sandberg, Rickard
AU - Lendahl, Urban
PY - 2015
Y1 - 2015
N2 - Decoding transcriptional effects of experimental tissue-tissue or cell-cell interactions is important; for example, to better understand tumor-stroma interactions after transplantation of human cells into mouse (xenografting). Transcriptome analysis of intermixed human and mouse cells has, however, frequently relied on the need to separate the two cell populations prior to transcriptome analysis, which introduces confounding effects on gene expression.
AB - Decoding transcriptional effects of experimental tissue-tissue or cell-cell interactions is important; for example, to better understand tumor-stroma interactions after transplantation of human cells into mouse (xenografting). Transcriptome analysis of intermixed human and mouse cells has, however, frequently relied on the need to separate the two cell populations prior to transcriptome analysis, which introduces confounding effects on gene expression.
UR - https://www.scopus.com/pages/publications/84938843679
U2 - 10.1186/s13058-015-0616-x
DO - 10.1186/s13058-015-0616-x
M3 - Article
C2 - 26265142
SN - 1465-5411
VL - 17
JO - Breast Cancer Research
JF - Breast Cancer Research
M1 - 109
ER -
