TY - JOUR
T1 - Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.
AU - Tivesten, Asa
AU - Vandenput, Liesbeth
AU - Carlzon, Daniel
AU - Nilsson, Maria
AU - Karlsson, Magnus
AU - Ljunggren, Osten
AU - Barrett-Connor, Elizabeth
AU - Mellström, Dan
AU - Ohlsson, Claes
PY - 2014
Y1 - 2014
N2 - The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid hormone in human blood. Its levels decline dramatically with age. Despite the great amount of literature on vascular and metabolic actions of DHEA/-S, evidence for an association between DHEA/-S levels and cardiovascular events is contradictory.
AB - The adrenal sex hormone dehydroepiandrosterone (DHEA), which is present in serum mainly as the sulfate DHEA-S, is the most abundant steroid hormone in human blood. Its levels decline dramatically with age. Despite the great amount of literature on vascular and metabolic actions of DHEA/-S, evidence for an association between DHEA/-S levels and cardiovascular events is contradictory.
U2 - 10.1016/j.jacc.2014.05.076
DO - 10.1016/j.jacc.2014.05.076
M3 - Article
C2 - 25443702
SN - 0735-1097
VL - 64
SP - 1801
EP - 1810
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 17
ER -