Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects.

Renata Gustafsson; Xanthi Stachtea; Marco Maccarana; Emma Grottling; Erik Eklund; Anders Malmström; Åke Oldberg

doi:10.1002/bdra.23300

Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects.

Renata Gustafsson, Xanthi Stachtea, Marco Maccarana, Emma Grottling, Erik Eklund, Anders Malmström, Åke Oldberg

Paediatrics (Lund)

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Abstract

Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduronic acid, produced by the two enzymes, DS-epimerase 1 and 2, which are encoded by Dse and Dsel, respectively.

Original language	English
Pages (from-to)	712-720
Journal	Birth Defects Research. Part A: Clinical and Molecular Teratology
Volume	100
Issue number	9
DOIs	https://doi.org/10.1002/bdra.23300
Publication status	Published - 2014

Subject classification (UKÄ)

Obstetrics, Gynecology and Reproductive Medicine

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10.1002/bdra.23300

Wiley-Blackwell__Gustafsson_et_al

http://www.ncbi.nlm.nih.gov/pubmed/25186462?dopt=Abstract

Cite this

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title = "Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects.",

abstract = "Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduronic acid, produced by the two enzymes, DS-epimerase 1 and 2, which are encoded by Dse and Dsel, respectively.",

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AU - Eklund, Erik

AU - Malmström, Anders

AU - Oldberg, Åke

PY - 2014

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AB - Dermatan sulfate (DS) is a highly sulfated polysaccharide with a variety of biological functions in extracellular matrix organization and processes such as tumorigenesis and wound healing. A distinct feature of DS is the presence of iduronic acid, produced by the two enzymes, DS-epimerase 1 and 2, which are encoded by Dse and Dsel, respectively.

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DO - 10.1002/bdra.23300

M3 - Article

C2 - 25186462

SN - 1542-0760

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JO - Birth Defects Research. Part A: Clinical and Molecular Teratology

JF - Birth Defects Research. Part A: Clinical and Molecular Teratology

IS - 9

ER -

Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects.

Abstract

Subject classification (UKÄ)

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