Desensitisation as a means of preventing untoward reactions to ionic contrast media

Carl-David Agardh, B Arner, S Ekholm, E Boijsen

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with a previous history of anaphylactic reactions to ionic iodinated contrast media were desensitised before a second radiologic examination was performed. The tolerance to the contrast medium was raised by repeated intravenous injections in increasing doses and concentrations. No serious side effects were noted when the examinations with contrast medium was repeated within a few days after the desensitisation. The positive effect of the desensitisation may depend on a successive consumption of complement proteins, probably responsible for the allergic reactions. Therefore, the available amount of complement for some days may be too low for the occurrence of a complement reaction.
Original languageEnglish
Pages (from-to)235-239
JournalActa Radiologica Diagnosis
Volume24
Issue number3
Publication statusPublished - 1983

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Unit on Vascular Diabetic Complications (013241510)

Subject classification (UKÄ)

  • Endocrinology and Diabetes

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