Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

Andréas Meijer

Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

Andréas Meijer

Centre for Analysis and Synthesis

Research output: Thesis › Doctoral Thesis (compilation)

Abstract

A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).

Original language	English
Qualification	Doctor
Awarding Institution	Centre for Analysis and Synthesis
Supervisors/Advisors	[unknown], [unknown], Supervisor, External person
Award date	2003 Dec 18
Publisher	Organic and Bioorganic Chemistry, Center for Chemistry and Chemical Engineering, Lund University
ISBN (Print)	91-628-5924-2
Publication status	Published - 2003

Bibliographical note

Defence details

Date: 2003-12-18
Time: 13:30
Place: Chemical center, hall K:B, Lund Institute of Technology.

External reviewer(s)

Name: Boons, Geert-Jan
Title: Professor
Affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, USA

---

Article: Paper I:Teddy Ercégovic; Andréas Meijer; Göran Magnusson; Ulf Ellervik;Iodine Monochloride/Silver Trifluoromethanesulfonate (ICl/AgOTf) as a convenient Promoter System for O-Glycoside SynthesisOrg. Lett. 2001, 3, 913

Article: Paper II:Andréas Meijer; Ulf Ellervik;Study of Interhalogens/Silver Trifluoromethanesulfonate as Promoter System for High-Yielding SialylationsJ. Org. Chem. 2002, 67, 7407

Article: Paper III:Andréas Meijer; Ulf Ellervik;Interhalogens (ICl/IBr) and AgOTf in thioglycoside activation; application in the synthesis of bis-lactam analogs of ganglioside GD3Preliminary manuscript

Article: Paper IV:Andréas Meijer; Ulf Ellervik;Direct aromatic iodination and bromination using interhalogens and Lewis acidsSubmitted

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)

Subject classification (UKÄ)

Organic Chemistry

Free keywords

GD3
Organic chemistry
bis-lactam
ganglioside
thioglycoside
promoter
iodine monobromide
glycosylation
iodine monochloride
Organisk kemi

Cite this

@phdthesis{ea227d50d6224f7d9752da0261feba30,

title = "Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam",

abstract = "A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).",

keywords = "GD3, Organic chemistry, bis-lactam, ganglioside, thioglycoside, promoter, iodine monobromide, glycosylation, iodine monochloride, Organisk kemi",

author = "Andr{\'e}as Meijer",

note = "Defence details Date: 2003-12-18 Time: 13:30 Place: Chemical center, hall K:B, Lund Institute of Technology. External reviewer(s) Name: Boons, Geert-Jan Title: Professor Affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, USA --- Article: Paper I:Teddy Erc{\'e}govic; Andr{\'e}as Meijer; G{\"o}ran Magnusson; Ulf Ellervik;Iodine Monochloride/Silver Trifluoromethanesulfonate (ICl/AgOTf) as a convenient Promoter System for O-Glycoside SynthesisOrg. Lett. 2001, 3, 913 Article: Paper II:Andr{\'e}as Meijer; Ulf Ellervik;Study of Interhalogens/Silver Trifluoromethanesulfonate as Promoter System for High-Yielding SialylationsJ. Org. Chem. 2002, 67, 7407 Article: Paper III:Andr{\'e}as Meijer; Ulf Ellervik;Interhalogens (ICl/IBr) and AgOTf in thioglycoside activation; application in the synthesis of bis-lactam analogs of ganglioside GD3Preliminary manuscript Article: Paper IV:Andr{\'e}as Meijer; Ulf Ellervik;Direct aromatic iodination and bromination using interhalogens and Lewis acidsSubmitted The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)",

year = "2003",

language = "English",

isbn = "91-628-5924-2",

publisher = "Organic and Bioorganic Chemistry, Center for Chemistry and Chemical Engineering, Lund University",

type = "Doctoral Thesis (compilation)",

school = "Centre for Analysis and Synthesis",

}

TY - THES

T1 - Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

AU - Meijer, Andréas

N1 - Defence details Date: 2003-12-18 Time: 13:30 Place: Chemical center, hall K:B, Lund Institute of Technology. External reviewer(s) Name: Boons, Geert-Jan Title: Professor Affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, USA --- Article: Paper I:Teddy Ercégovic; Andréas Meijer; Göran Magnusson; Ulf Ellervik;Iodine Monochloride/Silver Trifluoromethanesulfonate (ICl/AgOTf) as a convenient Promoter System for O-Glycoside SynthesisOrg. Lett. 2001, 3, 913 Article: Paper II:Andréas Meijer; Ulf Ellervik;Study of Interhalogens/Silver Trifluoromethanesulfonate as Promoter System for High-Yielding SialylationsJ. Org. Chem. 2002, 67, 7407 Article: Paper III:Andréas Meijer; Ulf Ellervik;Interhalogens (ICl/IBr) and AgOTf in thioglycoside activation; application in the synthesis of bis-lactam analogs of ganglioside GD3Preliminary manuscript Article: Paper IV:Andréas Meijer; Ulf Ellervik;Direct aromatic iodination and bromination using interhalogens and Lewis acidsSubmitted The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)

PY - 2003

Y1 - 2003

N2 - A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).

AB - A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).

KW - GD3

KW - Organic chemistry

KW - bis-lactam

KW - ganglioside

KW - thioglycoside

KW - promoter

KW - iodine monobromide

KW - glycosylation

KW - iodine monochloride

KW - Organisk kemi

M3 - Doctoral Thesis (compilation)

SN - 91-628-5924-2

PB - Organic and Bioorganic Chemistry, Center for Chemistry and Chemical Engineering, Lund University

ER -

Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

Abstract

Bibliographical note

Subject classification (UKÄ)

Free keywords

Fingerprint

Cite this