TY - JOUR
T1 - Diminished white matter integrity in patients with systemic lupus erythematosus.
AU - Schmidt-Wilcke, Tobias
AU - Cagnoli, Patricia
AU - Wang, Page
AU - Schultz, Thomas
AU - Lotz, Anne
AU - Mccune, William J
AU - Sundgren, Pia
PY - 2014
Y1 - 2014
N2 - Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that can affect the central nervous system. Neuropsychiatric symptoms are found in 25-70% of patients. Using diffusion tensor imaging (DTI) various studies have reported changes in white matter integrity in SLE patients with neuropsychiatric symptoms (NPSLE patients). The purpose of this study was to investigate, if regional changes in white matter integrity can also be detected in SLE patients without neuropsychiatric symptoms (non-NPSLE patients).
AB - Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that can affect the central nervous system. Neuropsychiatric symptoms are found in 25-70% of patients. Using diffusion tensor imaging (DTI) various studies have reported changes in white matter integrity in SLE patients with neuropsychiatric symptoms (NPSLE patients). The purpose of this study was to investigate, if regional changes in white matter integrity can also be detected in SLE patients without neuropsychiatric symptoms (non-NPSLE patients).
U2 - 10.1016/j.nicl.2014.07.001
DO - 10.1016/j.nicl.2014.07.001
M3 - Article
C2 - 25161895
SN - 2213-1582
VL - 5
SP - 291
EP - 297
JO - NeuroImage: Clinical
JF - NeuroImage: Clinical
ER -