Do we Still Need Human Embryonic Stem Cells for Stem Cell-Based Therapies? Epistemic and Ethical Aspects.

Kristina Hug; Göran Hermerén

doi:10.1007/s12015-011-9257-3

Do we Still Need Human Embryonic Stem Cells for Stem Cell-Based Therapies? Epistemic and Ethical Aspects.

Kristina Hug, Göran Hermerén

Medical Ethics

Research output: Contribution to journal › Article › peer-review

Abstract

While scientific community disagrees about similarities and differences between human embryonic stem (hES) cells and human induced pluripotent stem (hiPS) cells, some politicians embrace translational hiPS cell research as a replacement for translational hES cell research. We examine the ethical relevance of the main differences between hES and hiPS cell-based therapies and discuss whether, given the current state of knowledge, certain differences are essential. We discuss whether well-founded preferences can be made in hypothetical scenarios with varying levels of patient safety, treatment efficacy, treatment accessibility and ethical controversy.

Original language	English
Pages (from-to)	761-774
Journal	Stem Cell Reviews and Reports
Volume	7
DOIs	https://doi.org/10.1007/s12015-011-9257-3
Publication status	Published - 2011

Subject classification (UKÄ)

Cell and Molecular Biology

Access to Document

10.1007/s12015-011-9257-3

http://www.ncbi.nlm.nih.gov/pubmed/21461713?dopt=Abstract

1 Doctoral Thesis (compilation)

Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research
Hug, K., 2012, Department of Medical Ethics, Lund University. 150 p.
Research output: Thesis › Doctoral Thesis (compilation)

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Cite this

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abstract = "While scientific community disagrees about similarities and differences between human embryonic stem (hES) cells and human induced pluripotent stem (hiPS) cells, some politicians embrace translational hiPS cell research as a replacement for translational hES cell research. We examine the ethical relevance of the main differences between hES and hiPS cell-based therapies and discuss whether, given the current state of knowledge, certain differences are essential. We discuss whether well-founded preferences can be made in hypothetical scenarios with varying levels of patient safety, treatment efficacy, treatment accessibility and ethical controversy.",

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AU - Hermerén, Göran

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N2 - While scientific community disagrees about similarities and differences between human embryonic stem (hES) cells and human induced pluripotent stem (hiPS) cells, some politicians embrace translational hiPS cell research as a replacement for translational hES cell research. We examine the ethical relevance of the main differences between hES and hiPS cell-based therapies and discuss whether, given the current state of knowledge, certain differences are essential. We discuss whether well-founded preferences can be made in hypothetical scenarios with varying levels of patient safety, treatment efficacy, treatment accessibility and ethical controversy.

AB - While scientific community disagrees about similarities and differences between human embryonic stem (hES) cells and human induced pluripotent stem (hiPS) cells, some politicians embrace translational hiPS cell research as a replacement for translational hES cell research. We examine the ethical relevance of the main differences between hES and hiPS cell-based therapies and discuss whether, given the current state of knowledge, certain differences are essential. We discuss whether well-founded preferences can be made in hypothetical scenarios with varying levels of patient safety, treatment efficacy, treatment accessibility and ethical controversy.

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DO - 10.1007/s12015-011-9257-3

M3 - Article

SN - 2629-3269

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JO - Stem Cell Reviews and Reports

JF - Stem Cell Reviews and Reports

ER -

Do we Still Need Human Embryonic Stem Cells for Stem Cell-Based Therapies? Epistemic and Ethical Aspects.

Abstract

Subject classification (UKÄ)

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Research output

Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research

Cite this