TY - JOUR
T1 - Drug delivery to retinal photoreceptors
AU - Himawan, Erico
AU - Ekström, Per
AU - Buzgo, Matej
AU - Gaillard, Pieter
AU - Stefánsson, Einar
AU - Marigo, Valeria
AU - Loftsson, Thorsteinn
AU - Paquet-Durand, François
PY - 2019
Y1 - 2019
N2 - The photoreceptors of the retina are afflicted by diseases that still often lack satisfactory treatment options. Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.
AB - The photoreceptors of the retina are afflicted by diseases that still often lack satisfactory treatment options. Although suitable drugs might be available in some cases, the delivery of these compounds into the eye and across the blood–retinal barrier remains a significant challenge for therapy development. Here, we review the routes of drug administration to the retina and highlight different options for drug delivery to the photoreceptor cells.
U2 - 10.1016/j.drudis.2019.03.004
DO - 10.1016/j.drudis.2019.03.004
M3 - Review article
C2 - 30877076
AN - SCOPUS:85063296590
VL - 24
SP - 1637
EP - 1643
JO - Drug Discovery Today
JF - Drug Discovery Today
SN - 1878-5832
IS - 8
ER -