Early diagnostic value of Bcl-3 localization in colorectal cancer.

Karunakar Saamarthy, Sofie Björner, Martin Johansson, Göran Landberg, Ramin Massoumi, Karin Jirström, Katarzyna Masoumi

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Abstract

B-cell leukemia 3 (Bcl-3) is a member of the inhibitor of κB family, which regulates a wide range of biological processes by functioning as a transcriptional activator or as a repressor of target genes. Elevated expression, sustained nuclear accumulation, and uncontrolled activation of Bcl-3 causes increased cellular proliferation or survival, dependent on the tissue and type of stimuli.
Original languageEnglish
Article number341
JournalBMC Cancer
Volume15
Issue number1
DOIs
Publication statusPublished - 2015

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Division of Translational Cancer Research (013250500), Pathology (Malmö) (013031000), Clinical pathology, Malmö (013017551), Pathology, (Lund) (013030000)

Subject classification (UKÄ)

  • Cancer and Oncology

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