Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol

Johan Thörne, Sten Blomquist, Olle Elmér, Bo-Anders Jönsson, Sten Lindahl, Sven-Erik Strand

Research output: Contribution to journalArticlepeer-review

Abstract

Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims
Original languageEnglish
Pages (from-to)216-220
JournalThe American Journal of Surgery
Volume151
Issue number2
DOIs
Publication statusPublished - 1986

Subject classification (UKÄ)

  • Surgery

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