Early response to inhaled bronchodilators and corticosteroids as a predictor of 12-month treatment responder status and COPD exacerbations.

Peter M Calverley, Dirkje S Postma, Antonio R Anzueto, Barry J Make, Göran Eriksson, Stefan Peterson, Christine R Jenkins

Research output: Contribution to journalArticlepeer-review

Abstract

Early treatment response markers, for example, improvement in forced expiratory volume in 1 second (FEV1) and St George's Respiratory Questionnaire (SGRQ) total score, may help clinicians to better manage patients with chronic obstructive pulmonary disease (COPD). We investigated the prevalence of clinically important improvements in FEV1 and SGRQ scores after 2-month budesonide/formoterol or formoterol treatment and whether such improvements predict subsequent improvements and exacerbation rates.
Original languageEnglish
Pages (from-to)381-390
JournalThe International Journal of Chronic Obstructive Pulmonary Disease
Volume11
DOIs
Publication statusPublished - 2016

Subject classification (UKÄ)

  • Respiratory Medicine and Allergy

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