Effects of different colloid infusions on ROTEM and Multiplate during elective brain tumour neurosurgery.

N Li; Svajunas Statkevicius; Bogi Asgeirsson; Ulf Schött

doi:10.1186/s13741-015-0019-7

Effects of different colloid infusions on ROTEM and Multiplate during elective brain tumour neurosurgery.

N Li, Svajunas Statkevicius, Bogi Asgeirsson, Ulf Schött

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Abstract

The European Medicines Agency does not recommend the use of hydroxyethyl starch-based volume replacement solutions in critically ill patients due to an increased risk of renal failure. However, this recommendation is questionable for its perioperative use. Several recent randomised controlled studies do not indicate a risk for renal failure-not even after high-risk surgery. Human albumin is used in our neurointensive care unit as a part of the "Lund concept" of brain injury resuscitation, and albumin has been introduced in elective neurosurgery instead of starch. The aim of our prospective unblinded observational cohort study was to compare the degree of dilutive coagulopathy after albumin and starch intra-operative fluid therapy.

Original language	English
Article number	9
Journal	Perioperative Medicine
Volume	4
DOIs	https://doi.org/10.1186/s13741-015-0019-7
Publication status	Published - 2015

Subject classification (UKÄ)

Anesthesiology and Intensive Care

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/s13741-015-0019-7

BMC_Statkevicius_et_al

http://www.ncbi.nlm.nih.gov/pubmed/26425342?dopt=Abstract

Koagulation vid kirurgi och kritisk sjukdom
Schött, U. (PI)
1990/05/01 → 2019/03/31
Project: Research

Cite this

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title = "Effects of different colloid infusions on ROTEM and Multiplate during elective brain tumour neurosurgery.",

abstract = "The European Medicines Agency does not recommend the use of hydroxyethyl starch-based volume replacement solutions in critically ill patients due to an increased risk of renal failure. However, this recommendation is questionable for its perioperative use. Several recent randomised controlled studies do not indicate a risk for renal failure-not even after high-risk surgery. Human albumin is used in our neurointensive care unit as a part of the {"}Lund concept{"} of brain injury resuscitation, and albumin has been introduced in elective neurosurgery instead of starch. The aim of our prospective unblinded observational cohort study was to compare the degree of dilutive coagulopathy after albumin and starch intra-operative fluid therapy.",

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AU - Li, N

AU - Statkevicius, Svajunas

AU - Asgeirsson, Bogi

AU - Schött, Ulf

PY - 2015

Y1 - 2015

N2 - The European Medicines Agency does not recommend the use of hydroxyethyl starch-based volume replacement solutions in critically ill patients due to an increased risk of renal failure. However, this recommendation is questionable for its perioperative use. Several recent randomised controlled studies do not indicate a risk for renal failure-not even after high-risk surgery. Human albumin is used in our neurointensive care unit as a part of the "Lund concept" of brain injury resuscitation, and albumin has been introduced in elective neurosurgery instead of starch. The aim of our prospective unblinded observational cohort study was to compare the degree of dilutive coagulopathy after albumin and starch intra-operative fluid therapy.

AB - The European Medicines Agency does not recommend the use of hydroxyethyl starch-based volume replacement solutions in critically ill patients due to an increased risk of renal failure. However, this recommendation is questionable for its perioperative use. Several recent randomised controlled studies do not indicate a risk for renal failure-not even after high-risk surgery. Human albumin is used in our neurointensive care unit as a part of the "Lund concept" of brain injury resuscitation, and albumin has been introduced in elective neurosurgery instead of starch. The aim of our prospective unblinded observational cohort study was to compare the degree of dilutive coagulopathy after albumin and starch intra-operative fluid therapy.

U2 - 10.1186/s13741-015-0019-7

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JF - Perioperative Medicine

M1 - 9

ER -

Effects of different colloid infusions on ROTEM and Multiplate during elective brain tumour neurosurgery.

Abstract

Subject classification (UKÄ)

UN SDGs

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Projects

Koagulation vid kirurgi och kritisk sjukdom

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