Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.

Axel Nelson; Svajunas Statkevicius; Ulf Schött; Pär I Johansson; Peter Bentzer

doi:10.1186/s40635-016-0080-7

Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.

Axel Nelson, Svajunas Statkevicius, Ulf Schött, Pär I Johansson, Peter Bentzer

Research output: Contribution to journal › Article › peer-review

Abstract

Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.

Original language	English
Article number	6
Journal	Intensive Care Medicine Experimental
Volume	4
Issue number	6
DOIs	https://doi.org/10.1186/s40635-016-0080-7
Publication status	Published - 2016

Subject classification (UKÄ)

Anesthesiology and Intensive Care

Access to Document

10.1186/s40635-016-0080-7

http://www.ncbi.nlm.nih.gov/pubmed/26940500?dopt=Abstract

Koagulation vid kirurgi och kritisk sjukdom
Schött, U. (PI)
1990/05/01 → 2019/03/31
Project: Research

Cite this

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title = "Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.",

abstract = "Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.",

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AU - Nelson, Axel

AU - Statkevicius, Svajunas

AU - Schött, Ulf

AU - Johansson, Pär I

AU - Bentzer, Peter

PY - 2016

Y1 - 2016

N2 - Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.

AB - Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.

U2 - 10.1186/s40635-016-0080-7

DO - 10.1186/s40635-016-0080-7

M3 - Article

C2 - 26940500

SN - 2197-425X

VL - 4

JO - Intensive Care Medicine Experimental

JF - Intensive Care Medicine Experimental

IS - 6

M1 - 6

ER -

Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.

Abstract

Subject classification (UKÄ)

Access to Document

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Projects

Koagulation vid kirurgi och kritisk sjukdom

Cite this