Abstract
Cartilage oligomeric matrix protein was isolated in the native state from the Swarm rat chondrosarcoma. A crucial step was its selective extraction with EDTA-containing buffer. The purified protein was subjected to electron microscopy using rotary shadowing and negative stain. The images allowed the construction of a structural model. The bouquet-like protein consists of five 28-nm-long arms containing a peripheral globular domain, a flexible strand, and a central assembly domain, where the five arms meet in a cylindrical structure.
| Original language | English |
|---|---|
| Pages (from-to) | 6137-6141 |
| Journal | Journal of Biological Chemistry |
| Volume | 267 |
| Issue number | 9 |
| Publication status | Published - 1992 |
Bibliographical note
The information about affiliations in this record was updated in December 2015.The record was previously connected to the following departments: Connective Tissue Biology (013230151), Division of Infection Medicine (BMC) (013024020)
Subject classification (UKÄ)
- Infectious Medicine
- Clinical Medicine