Elevated level of wnt5a protein in localized prostate cancer tissue is associated with better outcome.

Azharuddin Sajid Syed Khaja, Leszek Helczynski, Anders Edsjö, Roy Ehrnström, Anna Lindgren, David Ulmert, Tommy Andersson, Anders Bjartell

Research output: Contribution to journalArticlepeer-review

37 Citations (SciVal)
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Abstract

Wnt5a is a non-canonical secreted glycoprotein of the Wnt family that plays an important role in cancer development and progression. Previous studies report that Wnt5a is upregulated in prostate cancer and suggested that Wnt5a affects migration and invasion of prostate tumor cell. This study aimed to evaluate the prognostic value of Wnt5a protein expression in prostate cancer tissue and its potential to predict outcome after radical prostatectomy in patients with localized prostate cancer.
Original languageEnglish
Article numbere26539
JournalPLoS ONE
Volume6
Issue number10
DOIs
Publication statusPublished - 2011

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Pathology (Malmö) (013031000), Division of Urological Cancers (013243420), Molecular Medicine (013031200), Clinical Chemistry, Malmö (013016000), Experimental Pathology (013031100)

Subject classification (UKÄ)

  • Cancer and Oncology

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