Endocytosis of therapeutic macromolecules in tumor cells - Mechanistic aspects of the proteoglycan receptor function

Breastcancer-genetics

Research output: Thesis › Doctoral Thesis (compilation)

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2008
Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation.
Welch, J. E., Bengtson, P., Svensson, K., Wittrup, A., Jenniskens, G. J., Ten Dam, G. B., Van Kuppevelt, T. H. & Belting, M., 2008, In: International Journal of Oncology. 32, 4, p. 749-756
Research output: Contribution to journal › Article › peer-review
2007
Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis
Wittrup, A., Sandgren, S., Welch, J., Welinder, C., Gustavsson, N., Mörgelin, M. & Belting, M., 2007 Sept 21, In: Journal of Biological Chemistry. 282, 38, p. 27897-27904 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2004
The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis
Sandgren, S., Wittrup, A., Cheng, F., Jönsson, M., Eklund, E., Busch, S. & Belting, M., 2004, In: Journal of Biological Chemistry. 279, 17, p. 17951-17956
Research output: Contribution to journal › Article › peer-review

Open Access