Evaluation of a novel method of noise reduction using computer-simulated mammograms

Oleg Tischenko, Christoph Hoeschen, David R. Dance, Roger A. Hunt, Andrew D.A. Maidment, Predrag R. Bakic

Research output: Contribution to journalArticlepeer-review

Abstract

A novel method of noise reduction has been tested for mammography using computer-simulated images for which the truth is known exactly. This method is based on comparing two images. The images are compared at different scales, using a cross-correlation function as a measure of similarity to define the image modifications in the wavelet domain. The computer-simulated images were calculated for noise-free primary radiation using a quasi-realistic voxel phantom. Two images corresponding to slightly different geometry were produced. Gaussian noise was added with certain properties to simulate quantum noise. The added noise could be reduced by >70% using the proposed method without any noticeable corruption of the structures. It is possible to save 50% dose in mammography by producing two images (each 25% of the dose for a standard mammogram). Additionally, a reduction of the anatomical noise and, therefore, better detection rates of breast cancer in mammography are possible.

Original languageEnglish
Pages (from-to)81-84
Number of pages4
JournalRadiation Protection Dosimetry
Volume114
Issue number1-3
DOIs
Publication statusPublished - 2005
Externally publishedYes

Subject classification (UKÄ)

  • Medical Engineering

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