Evaluation of breathing interplay effects during VMAT by using 3D gel measurements

Sofie Ceberg, Crister Ceberg, M. Falk, P. Munk af Rosenschold, Sven Bäck

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review


Respiratory motion during dynamic radiotherapy may affect the absorbed dose distribution both by dose-reducing smoothing and by more complicated interplay effects. In this study we present a novel method to determine the relative importance of these two effects. For the two dynamic deliveries studied in this work, the expected target dose reduction due to the smoothing effect was estimated by measurements convolved by the motion function. Remaining absorbed dose differences were attributed to interplay effects between the motion of the gel phantom and the movement of the modulating MLC leaves during modulated arc radiotherapy. The total dosimetric effect due to breathing motion and dynamic MLC motion during VMAT delivery resulted in an average of about 4% target dose reduction. Comparing with only the smoothing effect, the average difference was decreased to around 1%, and the remaining distribution was attributed to interplay effects. Although the interplay effects were small compared to the smoothing effect, the standard deviations of 1.4-2.3% (1SD) were larger than the narrow distribution for repeated stationary measurement with a standard deviation between 0.5-0.9% (1SD).
Original languageEnglish
Title of host publication7th International Conference on 3D Radiation Dosimetry (IC3DDose)
PublisherIOP Publishing
Publication statusPublished - 2013
Event7th International Conference on 3D Radiation Dosimetry (IC3DDose) - Sydney, Australia
Duration: 2012 Nov 42012 Nov 8

Publication series

ISSN (Print)1742-6596
ISSN (Electronic)1742-6588


Conference7th International Conference on 3D Radiation Dosimetry (IC3DDose)

Subject classification (UKÄ)

  • Radiology, Nuclear Medicine and Medical Imaging


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