Evidence for nonpoliovirus enterovirus multiplication in L20B cells

Luis Sarmiento Pérez, Pedro Más Lago, Rosa Palomera Puentes, Luis Morier Díaz, Magile Fonseca Quintana, Sonia Resik Aguirre

Research output: Contribution to journalArticlepeer-review

Abstract

Stool specimens collected from 1 515 healthy children following a mass vaccination campaign in Cuba were tested for poliovirus excretion using L20B cell lines. In spite of the selectivity of this cell line for polioviruses (117/129; 90.7%) some other nonpolio enteroviruses (12/129: 9.3%), such as coxsackie A virus types 4, 8 and 10, can grow in L20B cells.

Original languageEnglish
Pages (from-to)98-101
Number of pages4
JournalRevista cubana de medicina tropical
Volume59
Issue number2
Publication statusPublished - 2007 May 1
Externally publishedYes

Subject classification (UKÄ)

  • Cell and Molecular Biology

Free keywords

  • Animals
  • Capsid Proteins/genetics
  • Cell Line
  • Child
  • Cytopathogenic Effect, Viral
  • DNA, Viral/genetics
  • Enterovirus/classification
  • Feces/virology
  • Host Specificity
  • Humans
  • Mice
  • Mice, Transgenic
  • Phylogeny
  • Poliovirus Vaccine, Oral
  • Receptors, Virus/analysis
  • Vaccination
  • Virus Replication

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