Exposure to air pollution during pregnancy and health risks for mother and child

Research output: ThesisDoctoral Thesis (compilation)

719 Downloads (Pure)

Abstract

We had in the present thesis the unique possibility to use, in a socio-economically relatively homogenous population, high quality registry information on a population-based birth cohort (84 039 births during the period 1999-2005) in Scania (Skåne), the most Southern county of Sweden. The aim of the thesis was to investigate whether exposure to air pollution, in an area of low-levels exposures, during different periods of the pregnancy was associated with birth outcomes, pregnancy complications and risk of the child to develop type I diabetes (T1D). For all outcomes air pollution was assessed as nitrogen oxides (NOx) and traffic exposure. For T1D we also assessed the association with exposures to ozone.
We did not find any consistent associations between air pollution and birth outcomes, whereas an increased prevalence of gestational diabetes and preeclampsia with increasing NOx exposure was observed. We did also find that the risk of developing T1D increased if the mother had lived in areas of elevated levels of NOx during third trimester or ozone during second trimester. Our studies suggest that air pollution during pregnancy might be a health risk for mother and child, even at levels below current air quality guidelines.
Original languageEnglish
QualificationDoctor
Awarding Institution
  • Division of Occupational and Environmental Medicine, Lund University
Supervisors/Advisors
  • Rylander, Lars, Supervisor
  • Rignell-Hydbom, Anna, Supervisor
  • Tinnerberg, Håkan, Supervisor
Award date2014 Feb 28
Publisher
ISBN (Print)978-91-87651-43-4
Publication statusPublished - 2014

Bibliographical note

Defence details

Date: 2014-02-28
Time: 09:15
Place: Pufendorf Institute, Sölvegatan 2, Lund

External reviewer(s)

Name: Raaschou-Nielsen, Ole
Title: [unknown]
Affiliation: Danish Cancer Society

---

Subject classification (UKÄ)

  • Environmental Health and Occupational Health

Keywords

  • air pollution
  • pregnancy
  • birth outcomes
  • ozone modeeling
  • preeclampsia
  • Type1 Diabetes

Fingerprint

Dive into the research topics of 'Exposure to air pollution during pregnancy and health risks for mother and child'. Together they form a unique fingerprint.

Cite this