Expression of cyclin d1 and its association with disease characteristics in bladder cancer.

Pradeep Kopparapu, Stephen A Boorjian, Brian D Robinson, Martin Downes, Lorraine J Gudas, Nigel Mongan, Jenny L Persson

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: Invasive urothelial carcinoma of the bladder (UCB) is characterized by alterations in cell-cycle regulatory pathways. Defects in the expression of cyclin D1, a key cell-cycle regulator, have been implicated in progression of various types of cancer. In the present study, we investigated whether cyclin D1 expression is associated with clinicopathological parameters and whether it has any potential prognostic value in determining risk of UCB recurrence.
Original languageEnglish
Pages (from-to)5235-5242
JournalAnticancer research
Volume33
Issue number12
Publication statusPublished - 2013

Subject classification (UKÄ)

  • Cancer and Oncology

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