Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.

Alexandra R Morgan; Geoff J M Parker; Caleb Roberts; Giovanni A Buonaccorsi; Niall C Maguire; Penny L Hubbard Cristinacce; Dave Singh; Jørgen Vestbo; Leif Bjermer; Jonas Jögi; Ziad Taib; Janeli Sarv; Piet L B Bruijnzeel; Lars E Olsson; Eva Bondesson; Ulf Nihlén; Deirdre M McGrath; Simon S Young; John C Waterton; Lars H Nordenmark

doi:10.1016/j.ejrad.2014.08.004

Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.

Alexandra R Morgan, Geoff J M Parker, Caleb Roberts, Giovanni A Buonaccorsi, Niall C Maguire, Penny L Hubbard Cristinacce, Dave Singh, Jørgen Vestbo, Leif Bjermer, Jonas Jögi, Ziad Taib, Janeli Sarv, Piet L B Bruijnzeel, Lars E Olsson, Eva Bondesson, Ulf Nihlén, Deirdre M McGrath, Simon S Young, John C Waterton, Lars H Nordenmark

Research output: Contribution to journal › Article › peer-review

Abstract

Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests.

Original language	English
Pages (from-to)	2093-2101
Journal	European Journal of Radiology
Volume	83
Issue number	11
DOIs	https://doi.org/10.1016/j.ejrad.2014.08.004
Publication status	Published - 2014

Subject classification (UKÄ)

Radiology, Nuclear Medicine and Medical Imaging

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10.1016/j.ejrad.2014.08.004

http://www.ncbi.nlm.nih.gov/pubmed/25176287?dopt=Abstract

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Morgan, A. R., Parker, G. J. M., Roberts, C., Buonaccorsi, G. A., Maguire, N. C., Hubbard Cristinacce, P. L., Singh, D., Vestbo, J., Bjermer, L., Jögi, J., Taib, Z., Sarv, J., Bruijnzeel, P. L. B., Olsson, L. E., Bondesson, E., Nihlén, U., McGrath, D. M., Young, S. S., Waterton, J. C., & Nordenmark, L. H. (2014). Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD. European Journal of Radiology, 83(11), 2093-2101. https://doi.org/10.1016/j.ejrad.2014.08.004

@article{8f332c8810254ae18904cc237a68bcca,

title = "Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.",

abstract = "Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests.",

author = "Morgan, {Alexandra R} and Parker, {Geoff J M} and Caleb Roberts and Buonaccorsi, {Giovanni A} and Maguire, {Niall C} and {Hubbard Cristinacce}, {Penny L} and Dave Singh and J{\o}rgen Vestbo and Leif Bjermer and Jonas J{\"o}gi and Ziad Taib and Janeli Sarv and Bruijnzeel, {Piet L B} and Olsson, {Lars E} and Eva Bondesson and Ulf Nihl{\'e}n and McGrath, {Deirdre M} and Young, {Simon S} and Waterton, {John C} and Nordenmark, {Lars H}",

year = "2014",

doi = "10.1016/j.ejrad.2014.08.004",

language = "English",

volume = "83",

pages = "2093--2101",

journal = "European Journal of Radiology",

issn = "1872-7727",

publisher = "Elsevier",

number = "11",

}

Morgan, AR, Parker, GJM, Roberts, C, Buonaccorsi, GA, Maguire, NC, Hubbard Cristinacce, PL, Singh, D, Vestbo, J, Bjermer, L , Jögi, J, Taib, Z, Sarv, J, Bruijnzeel, PLB, Olsson, LE, Bondesson, E, Nihlén, U, McGrath, DM, Young, SS, Waterton, JC & Nordenmark, LH 2014, 'Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.', European Journal of Radiology, vol. 83, no. 11, pp. 2093-2101. https://doi.org/10.1016/j.ejrad.2014.08.004

TY - JOUR

T1 - Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.

AU - Morgan, Alexandra R

AU - Parker, Geoff J M

AU - Roberts, Caleb

AU - Buonaccorsi, Giovanni A

AU - Maguire, Niall C

AU - Hubbard Cristinacce, Penny L

AU - Singh, Dave

AU - Vestbo, Jørgen

AU - Bjermer, Leif

AU - Jögi, Jonas

AU - Taib, Ziad

AU - Sarv, Janeli

AU - Bruijnzeel, Piet L B

AU - Olsson, Lars E

AU - Bondesson, Eva

AU - Nihlén, Ulf

AU - McGrath, Deirdre M

AU - Young, Simon S

AU - Waterton, John C

AU - Nordenmark, Lars H

PY - 2014

Y1 - 2014

N2 - Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests.

AB - Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests.

U2 - 10.1016/j.ejrad.2014.08.004

DO - 10.1016/j.ejrad.2014.08.004

M3 - Article

C2 - 25176287

SN - 1872-7727

VL - 83

SP - 2093

EP - 2101

JO - European Journal of Radiology

JF - European Journal of Radiology

IS - 11

ER -

Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD.

Abstract

Subject classification (UKÄ)

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