Female genital mutilation of a karyotypic male presenting as a female with delayed puberty

M Ellaithi; Therese Nilsson; David Gisselsson Nord; A Elagib; H Eltigani; I Fadl-Elmula

doi:10.1186/1472-6874-6-6

Female genital mutilation of a karyotypic male presenting as a female with delayed puberty

M Ellaithi, Therese Nilsson, David Gisselsson Nord, A Elagib, H Eltigani, I Fadl-Elmula

Division of Clinical Genetics

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been discussed before. CASE PRESENTATION: The patient first presented as a female with delayed puberty. Hormonal analysis revealed a normal serum prolactin level of 215 Micro/L, a low FSH of 0.5 Micro/L, and a low LH of 1.1 Micro/L. Type IV FGM (Pharaonic circumcision) had been performed during childhood. Chromosomal analysis showed a 46, XY karyotype and ultrasonography verified a soft tissue structure in the position of the prostate. CONCLUSION: FGM pose a threat to the diagnosis and management of children with abnormal genital development in the Sudan and similar societies.

Original language	English
Journal	BMC Women's Health
Volume	6
Issue number	6
DOIs	https://doi.org/10.1186/1472-6874-6-6
Publication status	Published - 2006

Subject classification (UKÄ)

Public Health, Global Health, Social Medicine and Epidemiology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/1472-6874-6-6

Cite this

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title = "Female genital mutilation of a karyotypic male presenting as a female with delayed puberty",

abstract = "BACKGROUND: Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been discussed before. CASE PRESENTATION: The patient first presented as a female with delayed puberty. Hormonal analysis revealed a normal serum prolactin level of 215 Micro/L, a low FSH of 0.5 Micro/L, and a low LH of 1.1 Micro/L. Type IV FGM (Pharaonic circumcision) had been performed during childhood. Chromosomal analysis showed a 46, XY karyotype and ultrasonography verified a soft tissue structure in the position of the prostate. CONCLUSION: FGM pose a threat to the diagnosis and management of children with abnormal genital development in the Sudan and similar societies.",

author = "M Ellaithi and Therese Nilsson and {Gisselsson Nord}, David and A Elagib and H Eltigani and I Fadl-Elmula",

year = "2006",

doi = "10.1186/1472-6874-6-6",

language = "English",

volume = "6",

journal = "BMC Women's Health",

issn = "1472-6874",

publisher = "BioMed Central (BMC)",

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TY - JOUR

T1 - Female genital mutilation of a karyotypic male presenting as a female with delayed puberty

AU - Ellaithi, M

AU - Nilsson, Therese

AU - Gisselsson Nord, David

AU - Elagib, A

AU - Eltigani, H

AU - Fadl-Elmula, I

PY - 2006

Y1 - 2006

N2 - BACKGROUND: Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been discussed before. CASE PRESENTATION: The patient first presented as a female with delayed puberty. Hormonal analysis revealed a normal serum prolactin level of 215 Micro/L, a low FSH of 0.5 Micro/L, and a low LH of 1.1 Micro/L. Type IV FGM (Pharaonic circumcision) had been performed during childhood. Chromosomal analysis showed a 46, XY karyotype and ultrasonography verified a soft tissue structure in the position of the prostate. CONCLUSION: FGM pose a threat to the diagnosis and management of children with abnormal genital development in the Sudan and similar societies.

AB - BACKGROUND: Female genital mutilation (FGM) is commonly practiced mainly in a belt reaching from East to West Africa north of the equator. The practice is known across socio-economic classes and among different ethnic, religious, and cultural groups. Few studies have been appropriately designed to measure the health effects of FGM. However, the outcome of FGM on intersex individuals has never been discussed before. CASE PRESENTATION: The patient first presented as a female with delayed puberty. Hormonal analysis revealed a normal serum prolactin level of 215 Micro/L, a low FSH of 0.5 Micro/L, and a low LH of 1.1 Micro/L. Type IV FGM (Pharaonic circumcision) had been performed during childhood. Chromosomal analysis showed a 46, XY karyotype and ultrasonography verified a soft tissue structure in the position of the prostate. CONCLUSION: FGM pose a threat to the diagnosis and management of children with abnormal genital development in the Sudan and similar societies.

U2 - 10.1186/1472-6874-6-6

DO - 10.1186/1472-6874-6-6

M3 - Article

C2 - 16571108

SN - 1472-6874

VL - 6

JO - BMC Women's Health

JF - BMC Women's Health

IS - 6

ER -

Female genital mutilation of a karyotypic male presenting as a female with delayed puberty

Abstract

Subject classification (UKÄ)

UN SDGs

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