@inproceedings{64e293bdfb3e4e389b4f40a1806c949f,
title = "Fluorescence spectroscopy in tissue phantoms for improved depth resolution in tissue imaging",
abstract = "A way to determine the depth of an embedded fluorescent object, for example deep-lying tumors marked with a fluorescent probe, is to detect fluorescent light that has propagated through the medium at two different wavelength bands. A ratio can then be calculated between the corresponding intensities. The wavelength regions should be chosen such that there is a difference in the absorption in the medium. This spectral information could be used as a complement in other methods, for example in tomography, due to its straightforward implementation. In this study we have performed phantom measurements to determine the depth of a fluorescent object, filled with fluorophores. The transmission of yellow and red fluorescence was measured and a ratio of yellow to red fluorescence was calculated for several depths in tissue with a thickness of 2 cm. The ratio showed a clear dependence on the depth of the object",
keywords = "2 cm, yellow fluorescence, fluorophores, red fluorescence, phantom measurements, optical tomography, fluorescent light detection, fluorescent probe, deep-lying tumors, fluorescent object, tissue imaging, depth resolution, fluorescence spectroscopy, tissue phantoms",
author = "Jenny Svensson and A Garofalakis and H Meyer and Florian Forster and J Ripoll and Stefan Andersson-Engels",
year = "2005",
doi = "10.1117/12.632826",
language = "English",
volume = "5859",
publisher = "SPIE",
number = "1",
pages = "585906--1--585906--6",
booktitle = "Proceedings of the SPIE - The International Society for Optical Engineering",
address = "United States",
note = "Photon Migration and Diffuse-Light Imaging II ; Conference date: 12-06-2005",
}