Frequently Recurrent Takotsubo Syndrome in COPD

Juan Andres Vaz Leonidas, Rikard Berggren, Berne Eriksson

Research output: Contribution to journalArticlepeer-review


Cardiovascular disease is common among patients with chronic obstructive pulmonary disease (COPD). Takotsubo syndrome (TTS) is a transient cardiac disorder that, in its typical form, involves left ventricular dysfunction with apical ballooning and mimics acute coronary syndrome (ACS). "Bronchogenic TTS" has been proposed as a specific form of TTS (during severe acute dyspnea in asthma or COPD) with atypical presentation. Recurrent TTS in COPD seems to be exceptionally rare since only a handful of clinical cases have previously been reported in the literature. Here, we present a unique case of a frequently recurrent TTS during COPD exacerbation in a 70-year-old woman, with at least 4 different episodes of TTS within 5 years. This case report exemplifies the difficulties of the diagnosis of TTS at the onset of acute COPD exacerbation. Potential pathophysiological mechanisms and therapeutic strategies are also briefly discussed.

Original languageEnglish
Article number6706935
Pages (from-to)1-9
JournalCase reports in cardiology
Publication statusPublished - 2019 Jan 9
Externally publishedYes

Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems


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