From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

D. Hoogewijs; N. B. Terwilliger; K. A. Webster; J. A. Powell-Coffman; S. Tokishita; H. Yamagata; T. Hankeln; T. Burmester; K. T. Rytkonen; M. Nikinmaa; D. Abele; K. Heise; M. Lucassen; J. Fandrey; R. H. Maxwell; Sven Påhlman; T. A. Gorr

doi:10.1093/icb/icm072

From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

D. Hoogewijs, N. B. Terwilliger, K. A. Webster, J. A. Powell-Coffman, S. Tokishita, H. Yamagata, T. Hankeln, T. Burmester, K. T. Rytkonen, M. Nikinmaa, D. Abele, K. Heise, M. Lucassen, J. Fandrey, R. H. Maxwell, Sven Påhlman, T. A. Gorr

Department of Translational Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.

Original language	English
Pages (from-to)	552-577
Journal	Integrative and Comparative Biology
Volume	47
Issue number	4
DOIs	https://doi.org/10.1093/icb/icm072
Publication status	Published - 2007

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Molecular Medicine (013031200)

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/icb/icm072

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Hoogewijs, D., Terwilliger, N. B., Webster, K. A., Powell-Coffman, J. A., Tokishita, S., Yamagata, H., Hankeln, T., Burmester, T., Rytkonen, K. T., Nikinmaa, M., Abele, D., Heise, K., Lucassen, M., Fandrey, J., Maxwell, R. H., Påhlman, S., & Gorr, T. A. (2007). From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia. Integrative and Comparative Biology, 47(4), 552-577. https://doi.org/10.1093/icb/icm072

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title = "From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia",

abstract = "The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief {"}critters-to-cancer{"} survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.",

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note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Molecular Medicine (013031200)",

year = "2007",

doi = "10.1093/icb/icm072",

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volume = "47",

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journal = "Integrative and Comparative Biology",

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Hoogewijs, D, Terwilliger, NB, Webster, KA, Powell-Coffman, JA, Tokishita, S, Yamagata, H, Hankeln, T, Burmester, T, Rytkonen, KT, Nikinmaa, M, Abele, D, Heise, K, Lucassen, M, Fandrey, J, Maxwell, RH, Påhlman, S & Gorr, TA 2007, 'From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia', Integrative and Comparative Biology, vol. 47, no. 4, pp. 552-577. https://doi.org/10.1093/icb/icm072

TY - JOUR

T1 - From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

AU - Hoogewijs, D.

AU - Terwilliger, N. B.

AU - Webster, K. A.

AU - Powell-Coffman, J. A.

AU - Tokishita, S.

AU - Yamagata, H.

AU - Hankeln, T.

AU - Burmester, T.

AU - Rytkonen, K. T.

AU - Nikinmaa, M.

AU - Abele, D.

AU - Heise, K.

AU - Lucassen, M.

AU - Fandrey, J.

AU - Maxwell, R. H.

AU - Påhlman, Sven

AU - Gorr, T. A.

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Molecular Medicine (013031200)

PY - 2007

Y1 - 2007

N2 - The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.

AB - The objective of this symposium at the First International Congress of Respiratory Biology (ICRB) was to enhance communication between comparative biologists and cancer researchers working on O-2 sensing via the HIF pathway. Representatives from both camps came together on August 13-16, 2006, in Bonn, Germany, to discuss molecular adaptations that occur after cells have been challenged by a reduced (hypoxia) or completely absent (anoxia) supply of oxygen. This brief "critters-to-cancer" survey discusses current projects and new directions aimed at improving understanding of hypoxic signaling and developing therapeutic interventions.

U2 - 10.1093/icb/icm072

DO - 10.1093/icb/icm072

M3 - Article

C2 - 21672863

SN - 1557-7023

VL - 47

SP - 552

EP - 577

JO - Integrative and Comparative Biology

JF - Integrative and Comparative Biology

IS - 4

ER -

From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia

Abstract

Bibliographical note

Subject classification (UKÄ)

UN SDGs

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