Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells

Göran Bertilsson; Anna Falk; Jonas Frisén; Jessica  Heidrich; Kristina  Hellström; J Kortesmaa; Per Lindquist; Hanna  Lundh; Jacqueline McGuire; Alex  Mercer; Cesare Patrone; Harriet Rönnholm; Lilian  Wikström; Olof  Zachrisson

Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells

Göran Bertilsson (Inventor), Anna Falk (Inventor), Jonas Frisén (Inventor), Jessica Heidrich (Inventor), Kristina Hellström (Inventor), J Kortesmaa (Inventor), Per Lindquist (Inventor), Hanna Lundh (Inventor), Jacqueline McGuire (Inventor), Alex Mercer (Inventor), Cesare Patrone (Inventor), Harriet Rönnholm (Inventor), Lilian Wikström (Inventor), Olof Zachrisson (Inventor)

Karolinska Institute

Research output: Patent

Abstract

The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via PACAP, Maxadilan or VIP signaling. These methods are useful for reducing at least one symptom of the disorder.

Original language	English
Patent number	US Patent App. 10/291,171, 2003
IPC	2003/9/4 US 10291171
Publication status	Published - 2003
Externally published	Yes

Subject classification (UKÄ)

Neurosciences
Cell and Molecular Biology

Access to Document

https://worldwide.espacenet.com/patent/search/family/027502712/publication/US2003165485A1?q=pn%3DUS2003165485A1

Cite this

Bertilsson, G., Falk, A., Frisén, J., Heidrich, J., Hellström, K., Kortesmaa, J., Lindquist, P., Lundh, H., McGuire, J., Mercer, A., Patrone, C., Rönnholm, H., Wikström, L., & Zachrisson, O. (2003). Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells. (Patent No. US Patent App. 10/291,171, 2003). https://worldwide.espacenet.com/patent/search/family/027502712/publication/US2003165485A1?q=pn%3DUS2003165485A1

@misc{7b98ac8bdb2e484594310210aad1bebc,

title = "Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells",

abstract = "The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via PACAP, Maxadilan or VIP signaling. These methods are useful for reducing at least one symptom of the disorder.",

author = "G{\"o}ran Bertilsson and Anna Falk and Jonas Fris{\'e}n and Jessica Heidrich and Kristina Hellstr{\"o}m and J Kortesmaa and Per Lindquist and Hanna Lundh and Jacqueline McGuire and Alex Mercer and Cesare Patrone and Harriet R{\"o}nnholm and Lilian Wikstr{\"o}m and Olof Zachrisson",

year = "2003",

language = "English",

type = "Patent",

note = "US Patent App. 10/291,171, 2003; 2003/9/4 US 10291171",

}

Bertilsson, G, Falk, A, Frisén, J, Heidrich, J, Hellström, K, Kortesmaa, J, Lindquist, P, Lundh, H, McGuire, J, Mercer, A, Patrone, C, Rönnholm, H, Wikström, L & Zachrisson, O, Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells, Patent No. US Patent App. 10/291,171, 2003. <https://worldwide.espacenet.com/patent/search/family/027502712/publication/US2003165485A1?q=pn%3DUS2003165485A1>

TY - PAT

T1 - Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells

AU - Bertilsson, Göran

AU - Falk, Anna

AU - Frisén, Jonas

AU - Heidrich, Jessica

AU - Hellström, Kristina

AU - Kortesmaa, J

AU - Lindquist, Per

AU - Lundh, Hanna

AU - McGuire, Jacqueline

AU - Mercer, Alex

AU - Patrone, Cesare

AU - Rönnholm, Harriet

AU - Wikström, Lilian

AU - Zachrisson, Olof

PY - 2003

Y1 - 2003

N2 - The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via PACAP, Maxadilan or VIP signaling. These methods are useful for reducing at least one symptom of the disorder.

AB - The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via PACAP, Maxadilan or VIP signaling. These methods are useful for reducing at least one symptom of the disorder.

M3 - Patent

M1 - US Patent App. 10/291,171, 2003

ER -

Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Cite this