Genetic Characterization of Pediatric T-cell Acute Lymphoblastic Leukemia

Kristina Karrman

Division of Clinical Genetics

Research output: Thesis › Doctoral Thesis (compilation)

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3 Article
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2009
Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: Rare T-cell receptor gene rearrangements are associated with poor outcome.
Karrman, K., Forestier, E., Heyman, M., K Andersen, M., Autio, K., Blennow, E., Borgström, G., Ehrencrona, H., Golovleva, I., Heim, S., Heinonen, K., Hovland, R., Johannsson, J. H., Kerndrup, G., Nordgren, A., Palmqvist, L. & Johansson, B., 2009, In: Genes, Chromosomes and Cancer. 48, 9, p. 795-805
Research output: Contribution to journal › Article › peer-review
The t(X;7)(q22;q34) in paediatric T-cell acute lymphoblastic leukaemia results in overexpression of the insulin receptor substrate 4 gene through illegitimate recombination with the T-cell receptor beta locus.
Karrman, K., Kjeldsen, E., Lassen, C., Isaksson, M., Davidsson, J., Andersson, A., Hasle, H., Fioretos, T. & Johansson, B., 2009, In: British Journal of Haematology. 144, p. 546-551
Research output: Contribution to journal › Article › peer-review
2006

Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.
Karrman, K., Andersson, A., Björgvinsdottir, H., Strömbeck, B., Lassen, C., Olofsson, T., Nguyen-Khac, F., Berger, R., Bernard, O., Fioretos, T. & Johansson, B., 2006, In: European Journal of Haematology. 77, 1, p. 27-34
Research output: Contribution to journal › Article › peer-review