We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.
Subject classification (UKÄ)
- Medical Genetics
- Cancer and Oncology
- Expression quantitative trait locus
- Genome-wide association study
- Prostate cancer
- Survival analysis