Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.

Ulrika Andersson, Carl Wibom, Kristina Cederquist, Steina Aradottir, Åke Borg, Georgina N Armstrong, Sanjay Shete, Ching C Lau, Matthew N Bainbridge, Elizabeth B Claus, Jill Barnholtz-Sloan, Rose Lai, Dora Il'yasova, Richard S Houlston, Joellen Schildkraut, Jonine L Bernstein, Sara H Olson, Robert B Jenkins, Daniel H Lachance, Margaret WrenschFaith G Davis, Ryan Merrell, Christoffer Johansen, Siegal Sadetzki, Melissa L Bondy, Beatrice S Melin

Research output: Contribution to journalArticlepeer-review

11 Citations (SciVal)

Abstract

Although familial susceptibility to glioma is known, the genetic basis for this susceptibility remains unidentified in the majority of glioma-specific families. An alternative approach to identifying such genes is to examine cancer pedigrees, which include glioma as one of several cancer phenotypes, to determine whether common chromosomal modifications might account for the familial aggregation of glioma and other cancers.
Original languageEnglish
Pages (from-to)1333-1340
JournalNeuro-Oncology
Volume16
Issue number10
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Cancer and Oncology

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