TY - JOUR
T1 - Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalized Nutrition
T2 - Part 2 - Ethics, Challenges and Endeavors of Precision Nutrition
AU - Kohlmeier, Martin
AU - De Caterina, Raffaele
AU - Ferguson, Lynnette R.
AU - Görman, Ulf
AU - Allayee, Hooman
AU - Prasad, Chandan
AU - Kang, Jing X.
AU - Nicoletti, Carolina Ferreira
AU - Martinez, J. Alfredo
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Nutrigenetics considers the influence of individual genetic variation on differences in response to dietary components, nutrient requirements and predisposition to disease. Nutrigenomics involves the study of interactions between the genome and diet, including how nutrients affect the transcription and translation process plus subsequent proteomic and metabolomic changes, and also differences in response to dietary factors based on the individual genetic makeup. Personalized characteristics such as age, gender, physical activity, physiological state and social status, and special conditions such as pregnancy and risk of disease can inform dietary advice that more closely meets individual needs. Precision nutrition has a promising future in treating the individual according to their phenotype and genetic characteristics, aimed at both the treatment and prevention of disease. However, many aspects are still in progress and remain as challenges for the future of nutrition. The integration of the human genotype and microbiome needs to be better understood. Further advances in data interpretation tools are also necessary, so that information obtained through newer tests and technologies can be properly transferred to consumers. Indeed, precision nutrition will integrate genetic data with phenotypical, social, cultural and personal preferences and lifestyles matters to provide a more individual nutrition, but considering public health perspectives, where ethical, legal and policy aspects need to be defined and implemented.
AB - Nutrigenetics considers the influence of individual genetic variation on differences in response to dietary components, nutrient requirements and predisposition to disease. Nutrigenomics involves the study of interactions between the genome and diet, including how nutrients affect the transcription and translation process plus subsequent proteomic and metabolomic changes, and also differences in response to dietary factors based on the individual genetic makeup. Personalized characteristics such as age, gender, physical activity, physiological state and social status, and special conditions such as pregnancy and risk of disease can inform dietary advice that more closely meets individual needs. Precision nutrition has a promising future in treating the individual according to their phenotype and genetic characteristics, aimed at both the treatment and prevention of disease. However, many aspects are still in progress and remain as challenges for the future of nutrition. The integration of the human genotype and microbiome needs to be better understood. Further advances in data interpretation tools are also necessary, so that information obtained through newer tests and technologies can be properly transferred to consumers. Indeed, precision nutrition will integrate genetic data with phenotypical, social, cultural and personal preferences and lifestyles matters to provide a more individual nutrition, but considering public health perspectives, where ethical, legal and policy aspects need to be defined and implemented.
KW - Functional foods
KW - Genetic tests
KW - Nutrigenetics
KW - Nutrigenomics
KW - Nutriomics
KW - Omics
KW - Personalized nutrition
KW - Public health
U2 - 10.1159/000446347
DO - 10.1159/000446347
M3 - Article
C2 - 27286972
AN - SCOPUS:84975154472
SN - 1661-6499
VL - 9
SP - 28
EP - 46
JO - Journal of Nutrigenetics and Nutrigenomics
JF - Journal of Nutrigenetics and Nutrigenomics
IS - 1
ER -