Health-related quality of life in patients with pharyngeal carcinoma: A five-year follow-up.

Mats Nordgren, Magnus Jannert, Morten Boysen, Marianne Ahlner-Elmqvist, Ewa Silander, Kristin Bjordal, Eva Hammerlid

Research output: Contribution to journalArticlepeer-review

48 Citations (SciVal)

Abstract

Purpose. The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multi-center study. Methods. Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). Results. Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions and teeth increased between 1 and 5 years. The HRQL at diagnosis was associated with survival. Patients with oropharyngeal carcinoma reported better HRQL than patients with hypopharyngeal carcinoma. Conclusions. For patients with pharyngeal carcinoma, the HRQL at diagnosis seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of pharyngeal carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and thick secretions. (c) 2005 Wiley Periodicals, Inc.
Original languageEnglish
Pages (from-to)339-349
JournalHead and Neck
Volume28
Issue numberNov 14
DOIs
Publication statusPublished - 2006

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Disease of the Paranasal Sinus, Cancer and HRQL (013243520), Reconstructive Surgery (013240300)

Subject classification (UKÄ)

  • Surgery
  • Otorhinolaryngology

Keywords

  • pharyngeal carcinoma
  • longitudinal HRQL
  • EORTC QLQ-C30
  • predictive factors
  • EORTC
  • OLO-H&N35

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