TY - JOUR
T1 - Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit
AU - Dahlqvist, Jenny Alenius
AU - Karlsson, Marcus
AU - Wiklund, Urban
AU - Hornsten, Rolf
AU - Stromvall-Larsson, Eva
AU - Berggren, Hakan
AU - Hanséus, Katarina
AU - Johansson, Sune
AU - Rydberg, Annika
PY - 2012
Y1 - 2012
N2 - The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P < 0.0001), VLF (P < 0.0001), LF (P < 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was found in both the LT and EC patients. In terms of HRV reduction, EC was not superior to LT.
AB - The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P < 0.0001), VLF (P < 0.0001), LF (P < 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was found in both the LT and EC patients. In terms of HRV reduction, EC was not superior to LT.
KW - Extracardiac conduit
KW - Fontan circulation
KW - Heart rate variability
KW - Lateral tunnel
U2 - 10.1007/s00246-011-0126-2
DO - 10.1007/s00246-011-0126-2
M3 - Article
C2 - 21984213
SN - 0172-0643
VL - 33
SP - 307
EP - 315
JO - Pediatric Cardiology
JF - Pediatric Cardiology
IS - 2
ER -