@inbook{400b364c2fb741e8a4263284eb231022,
title = "Heat Sensitive Biosensors",
abstract = "The unsurpassed versatility of heat sensitive biosensors is illustrated by various new applications of the flow-calorimetric biosensor system, the enzyme thermistor (ET) developed in our laboratory. The ET measures the reaction heat in a small column containing immobilized biocatalyst. Since most biological reactions are exothermic, the ET has a very broad applicability and numerous assays of clinical as well as biotechnological interest have been studied. The procedure is well suited for monitoring and control of biotechnological processes due to its high operational stability. New results from this area are presented as well as developments on an automated thermometric immunoassay (TELISA). Miniaturized ET-devices are suitable for portable monitoring of, for instance, blood glucose. Other recent work include determinations in organic solvents, direct characterization of immobilized biocatalysts, and monitoring of bioactivities in solution.",
author = "Bengt Danielsson and Ulrika Hedberg and Morten Rank and Bin Xie",
year = "1993",
doi = "10.1007/978-94-011-1932-0_51",
language = "English",
isbn = "978-0-7923-2529-1",
volume = "252",
series = "NATO ASI Series",
publisher = "Springer",
pages = "541--548",
editor = "Guilbault, {George G.} and Marco Mascini",
booktitle = "Uses of Immobilized Biological Compounds",
address = "Germany",
}