Abstract
UNLABELLED: Graft infection is a serious complication to vascular surgery. The aim of this study was to assess (18)F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection.
METHODS: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for (18)F-FDG accumulation. Clinical and biochemical data were obtained from patient records.
RESULTS: High (18)F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation.
CONCLUSION: (18)F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by (18)F-FDG PET/CT is evident.
| Original language | English |
|---|---|
| Pages (from-to) | 1601-5 |
| Number of pages | 5 |
| Journal | Journal of Nuclear Medicine |
| Volume | 49 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2008 Oct |
| Externally published | Yes |
Subject classification (UKÄ)
- Radiology and Medical Imaging
- Cardiology and Cardiovascular Disease
Free keywords
- Aged
- Aged, 80 and over
- Aneurysm
- Aorta
- Aortic Aneurysm, Abdominal
- Blood Vessel Prosthesis
- Diagnostic Imaging
- Female
- Fluorodeoxyglucose F18
- Humans
- Male
- Middle Aged
- Positron-Emission Tomography
- Radiopharmaceuticals
- Tomography, X-Ray Computed
- Journal Article
- Research Support, Non-U.S. Gov't