High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

Andreas Edsfeldt; Eva Bengtsson; Giuseppe Asciutto; Pontus Dunér; Harry Björkbacka; Gunilla Nordin Fredrikson; Jan Nilsson; Isabel Goncalves

doi:10.1159/000443022

High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

Andreas Edsfeldt, Eva Bengtsson, Giuseppe Asciutto, Pontus Dunér, Harry Björkbacka, Gunilla Nordin Fredrikson, Jan Nilsson, Isabel Goncalves

Research output: Contribution to journal › Article › peer-review

Abstract

Galectin-3 (Gal-3) has been suggested to have both pro- and anti-atherogenic properties. High plasma Gal-3 levels are associated with increased risk for cardiovascular (CV) death. However, it has so far not been investigated if plasma Gal-3 levels can predict the risk for future stroke in patients suffering from carotid atherosclerosis. The aim of this study was to investigate whether Gal-3 could be used as a marker to predict postoperative cerebrovascular ischemic events among patients who underwent carotid endarterectomy (CEA).

Original language	English
Pages (from-to)	199-203
Journal	Cerebrovascular Diseases
Volume	41
Issue number	3-4
DOIs	https://doi.org/10.1159/000443022
Publication status	Published - 2016

Subject classification (UKÄ)

Cardiac and Cardiovascular Systems

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10.1159/000443022

http://www.ncbi.nlm.nih.gov/pubmed/26812165?dopt=Abstract

Cite this

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title = "High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.",

abstract = "Galectin-3 (Gal-3) has been suggested to have both pro- and anti-atherogenic properties. High plasma Gal-3 levels are associated with increased risk for cardiovascular (CV) death. However, it has so far not been investigated if plasma Gal-3 levels can predict the risk for future stroke in patients suffering from carotid atherosclerosis. The aim of this study was to investigate whether Gal-3 could be used as a marker to predict postoperative cerebrovascular ischemic events among patients who underwent carotid endarterectomy (CEA).",

author = "Andreas Edsfeldt and Eva Bengtsson and Giuseppe Asciutto and Pontus Dun{\'e}r and Harry Bj{\"o}rkbacka and {Nordin Fredrikson}, Gunilla and Jan Nilsson and Isabel Goncalves",

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doi = "10.1159/000443022",

language = "English",

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journal = "Cerebrovascular Diseases",

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T1 - High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

AU - Edsfeldt, Andreas

AU - Bengtsson, Eva

AU - Asciutto, Giuseppe

AU - Dunér, Pontus

AU - Björkbacka, Harry

AU - Nordin Fredrikson, Gunilla

AU - Nilsson, Jan

AU - Goncalves, Isabel

PY - 2016

Y1 - 2016

N2 - Galectin-3 (Gal-3) has been suggested to have both pro- and anti-atherogenic properties. High plasma Gal-3 levels are associated with increased risk for cardiovascular (CV) death. However, it has so far not been investigated if plasma Gal-3 levels can predict the risk for future stroke in patients suffering from carotid atherosclerosis. The aim of this study was to investigate whether Gal-3 could be used as a marker to predict postoperative cerebrovascular ischemic events among patients who underwent carotid endarterectomy (CEA).

AB - Galectin-3 (Gal-3) has been suggested to have both pro- and anti-atherogenic properties. High plasma Gal-3 levels are associated with increased risk for cardiovascular (CV) death. However, it has so far not been investigated if plasma Gal-3 levels can predict the risk for future stroke in patients suffering from carotid atherosclerosis. The aim of this study was to investigate whether Gal-3 could be used as a marker to predict postoperative cerebrovascular ischemic events among patients who underwent carotid endarterectomy (CEA).

U2 - 10.1159/000443022

DO - 10.1159/000443022

M3 - Article

C2 - 26812165

SN - 1421-9786

VL - 41

SP - 199

EP - 203

JO - Cerebrovascular Diseases

JF - Cerebrovascular Diseases

IS - 3-4

ER -

High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

Abstract

Subject classification (UKÄ)

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