Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.

Hannes Hartman Magnusson; Erik Wetterholm; Henrik Thorlacius; Sara Regnér

doi:10.1007/s10620-014-3474-y

Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.

Hannes Hartman Magnusson, Erik Wetterholm, Henrik Thorlacius, Sara Regnér

Surgery

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Abstract

The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are poorly understood.

Original language	English
Pages (from-to)	1284-1289
Journal	Digestive Diseases and Sciences
Volume	60
Issue number	5
DOIs	https://doi.org/10.1007/s10620-014-3474-y
Publication status	Published - 2015

Subject classification (UKÄ)

Gastroenterology and Hepatology

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10.1007/s10620-014-3474-y

http://www.ncbi.nlm.nih.gov/pubmed/25492506?dopt=Abstract

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title = "Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.",

abstract = "The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are poorly understood.",

author = "{Hartman Magnusson}, Hannes and Erik Wetterholm and Henrik Thorlacius and Sara Regn{\'e}r",

year = "2015",

doi = "10.1007/s10620-014-3474-y",

language = "English",

volume = "60",

pages = "1284--1289",

journal = "Digestive Diseases and Sciences",

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AU - Hartman Magnusson, Hannes

AU - Wetterholm, Erik

AU - Thorlacius, Henrik

AU - Regnér, Sara

PY - 2015

Y1 - 2015

N2 - The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are poorly understood.

AB - The onset of acute pancreatitis (AP) is characterized by early protease activation followed by inflammation and organ damage, but the mechanisms are poorly understood.

U2 - 10.1007/s10620-014-3474-y

DO - 10.1007/s10620-014-3474-y

M3 - Article

SN - 1573-2568

VL - 60

SP - 1284

EP - 1289

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

IS - 5

ER -

Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.

Abstract

Subject classification (UKÄ)

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