HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

Amr Al-Haidari; Ingvar Syk; Henrik Thorlacius

doi:10.1016/j.bbrc.2014.02.078

HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

Amr Al-Haidari, Ingvar Syk, Henrik Thorlacius

Surgery

Research output: Contribution to journal › Article › peer-review

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Abstract

Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.

Original language	English
Pages (from-to)	68-72
Journal	Biochemical and Biophysical Research Communications
Volume	446
Issue number	1
DOIs	https://doi.org/10.1016/j.bbrc.2014.02.078
Publication status	Published - 2014

Subject classification (UKÄ)

Biological Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bbrc.2014.02.078

Elsevier__Al-Haidari_et_al

http://www.ncbi.nlm.nih.gov/pubmed/24582560?dopt=Abstract

1 Doctoral Thesis (compilation)

Chemokine-Mediated Migration of Colon Cancer Cells
Al-Haidari, A., 2018, Lund: Lund University: Faculty of Medicine. 78 p.
Research output: Thesis › Doctoral Thesis (compilation)

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title = "HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.",

abstract = "Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.",

author = "Amr Al-Haidari and Ingvar Syk and Henrik Thorlacius",

year = "2014",

doi = "10.1016/j.bbrc.2014.02.078",

language = "English",

volume = "446",

pages = "68--72",

journal = "Biochemical and Biophysical Research Communications",

issn = "1090-2104",

publisher = "Elsevier",

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T1 - HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

AU - Al-Haidari, Amr

AU - Syk, Ingvar

AU - Thorlacius, Henrik

PY - 2014

Y1 - 2014

N2 - Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.

AB - Simvastatin is widely used to lower cholesterol levels in patients with cardiovascular diseases, although accumulating evidence suggests that statins, such as simvastatin, also exert numerous anti-tumoral effects.

U2 - 10.1016/j.bbrc.2014.02.078

DO - 10.1016/j.bbrc.2014.02.078

M3 - Article

C2 - 24582560

SN - 1090-2104

VL - 446

SP - 68

EP - 72

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 1

ER -

HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation.

Abstract

Subject classification (UKÄ)

UN SDGs

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Research output

Chemokine-Mediated Migration of Colon Cancer Cells

Cite this