Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins.

Mattias Levin; A M Davies; Maria Liljekvist; Fredrika Carlsson; H J Gould; B J Sutton; Mats Ohlin

doi:10.1111/cea.12230

Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins.

Mattias Levin, A M Davies, Maria Liljekvist, Fredrika Carlsson, H J Gould, B J Sutton, Mats Ohlin

Department of Immunotechnology

Research output: Contribution to journal › Article › peer-review

Abstract

The interaction between IgE and allergen is a key event at the initiation of an allergic response, and its characteristics have substantial effects on the clinical manifestation. Despite this, the molecular details of the interaction between human IgE and the major birch allergen Bet v 1, one of the most potent tree allergens, still remain poorly investigated.

Original language	English
Pages (from-to)	288-299
Journal	Clinical and Experimental Allergy
Volume	44
Issue number	2
DOIs	https://doi.org/10.1111/cea.12230
Publication status	Published - 2014

Subject classification (UKÄ)

Immunology in the Medical Area (including Cell and Immunotherapy)

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10.1111/cea.12230

Human IgE repertoires and an anti-allergome resource
Ohlin, M. (PI), Greiff, L. (PI) & Lindstedt, M. (PI)
Alfred Österlunds stiftelse, Stiftelsen Olle Engkvist Byggmästare, Swedish Research Council, Konsul Th C Berghs Stiftelse, National Institutes of Health, United States
2003/01/01 → …
Project: Research

Cite this

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abstract = "The interaction between IgE and allergen is a key event at the initiation of an allergic response, and its characteristics have substantial effects on the clinical manifestation. Despite this, the molecular details of the interaction between human IgE and the major birch allergen Bet v 1, one of the most potent tree allergens, still remain poorly investigated.",

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AU - Gould, H J

AU - Sutton, B J

AU - Ohlin, Mats

PY - 2014

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AB - The interaction between IgE and allergen is a key event at the initiation of an allergic response, and its characteristics have substantial effects on the clinical manifestation. Despite this, the molecular details of the interaction between human IgE and the major birch allergen Bet v 1, one of the most potent tree allergens, still remain poorly investigated.

U2 - 10.1111/cea.12230

DO - 10.1111/cea.12230

M3 - Article

C2 - 24447087

SN - 1365-2222

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JO - Clinical and Experimental Allergy

JF - Clinical and Experimental Allergy

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Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins.

Abstract

Subject classification (UKÄ)

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Human IgE repertoires and an anti-allergome resource

Cite this