Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

Magnus Paulsson; Birendra Singh; Al-Jubair Tamim; Yu-Ching Su; Niels Høiby; Kristian Riesbeck

doi:10.1016/j.jcf.2015.05.005

Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

Magnus Paulsson, Birendra Singh, Al-Jubair Tamim, Yu-Ching Su, Niels Høiby, Kristian Riesbeck

Clinical Microbiology, Malmö

Copenhagen University Hospital

Research output: Contribution to journal › Article › peer-review

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Abstract

Pseudomonas aeruginosa is a pathogen that frequently colonizes patients with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). Several pathogens are known to bind vitronectin to increase their virulence. Vitronectin has been shown to enhance P. aeruginosa adhesion to host epithelial cells.

Original language	English
Pages (from-to)	600-607
Journal	Journal of Cystic Fibrosis
Volume	14
Issue number	5
DOIs	https://doi.org/10.1016/j.jcf.2015.05.005
Publication status	Published - 2015

Subject classification (UKÄ)

Microbiology in the Medical Area

Access to Document

10.1016/j.jcf.2015.05.005

Elsevier_Paulsson_et_al

http://www.ncbi.nlm.nih.gov/pubmed/26047937?dopt=Abstract

1 Poster
1 Doctoral Thesis (compilation)

Host-Pathogen Interactions in Pseudomonas aeruginosa Invasive and Respiratory Tract Infection
Paulsson, M., 2017, Lund: Lund University: Faculty of Medicine. 84 p.
Research output: Thesis › Doctoral Thesis (compilation)

Open Access
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A novel vitronectin-binding protein of Pseudomonas aeruginosa for effective infection of the airways
Paulsson, M., Ringwood, T., Su, S. Y., Singh, B., Høiby, N. & Riesbeck, K., 2015 Apr 26, p. P0456.
Research output: Contribution to conference › Poster › peer-review

1 Active

The Extracellular Matrix in Patients with CF or COPD as a Basis for Novel Therapeutical Opportunities
Paulsson, M. (Researcher), Su, S. Y. (Researcher) & Riesbeck, K. (PI)
2018/01/01 → 2025/12/31
Project: Research

Cite this

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title = "Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa.",

abstract = "Pseudomonas aeruginosa is a pathogen that frequently colonizes patients with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). Several pathogens are known to bind vitronectin to increase their virulence. Vitronectin has been shown to enhance P. aeruginosa adhesion to host epithelial cells.",

author = "Magnus Paulsson and Birendra Singh and Al-Jubair Tamim and Yu-Ching Su and Niels H{\o}iby and Kristian Riesbeck",

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T1 - Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

AU - Paulsson, Magnus

AU - Singh, Birendra

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AU - Su, Yu-Ching

AU - Høiby, Niels

AU - Riesbeck, Kristian

PY - 2015

Y1 - 2015

N2 - Pseudomonas aeruginosa is a pathogen that frequently colonizes patients with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). Several pathogens are known to bind vitronectin to increase their virulence. Vitronectin has been shown to enhance P. aeruginosa adhesion to host epithelial cells.

AB - Pseudomonas aeruginosa is a pathogen that frequently colonizes patients with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). Several pathogens are known to bind vitronectin to increase their virulence. Vitronectin has been shown to enhance P. aeruginosa adhesion to host epithelial cells.

U2 - 10.1016/j.jcf.2015.05.005

DO - 10.1016/j.jcf.2015.05.005

M3 - Article

C2 - 26047937

SN - 1873-5010

VL - 14

SP - 600

EP - 607

JO - Journal of Cystic Fibrosis

JF - Journal of Cystic Fibrosis

IS - 5

ER -

Identification of outer membrane Porin D as a vitronectin-binding factor in cystic fibrosis clinical isolates of Pseudomonas aeruginosa.

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Research output

Host-Pathogen Interactions in Pseudomonas aeruginosa Invasive and Respiratory Tract Infection

A novel vitronectin-binding protein of Pseudomonas aeruginosa for effective infection of the airways

Projects

The Extracellular Matrix in Patients with CF or COPD as a Basis for Novel Therapeutical Opportunities

Cite this