IL-3 and IL-4 activate cyclic nucleotide phosphodiesterases 3 (PDE3) and 4 (PDE4) by different mechanisms in FDCP2 myeloid cells

Medicine & Life Sciences

• Cyclic Nucleotides 100%
• Interleukin-3 98%
• Phosphoric Diester Hydrolases 96%
• Myeloid Cells 85%
• Interleukin-4 77%
• Phosphatidylinositol 3-Kinase 50%
• Mitogen-Activated Protein Kinases 49%
• Insulin Receptor Substrate Proteins 43%
• Granulocytes 33%
• Mitogen-Activated Protein Kinase Kinases 27%
• alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 24%
• Tumor Necrosis Factor-alpha 23%
• Protein Kinase C 23%
• Macrophages 23%
• Tyrosine 23%
• Wortmannin 20%
• Phosphorylation 17%
• MAP Kinase Kinase 1 12%
• Janus Kinase Inhibitors 11%
• Protein C Inhibitor 9%
• Proto-Oncogene Proteins c-akt 9%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 9%
• Phorbol Esters 9%
• Protein Kinase Inhibitors 8%
• Transducers 8%
• Cytokines 5%
• Proteins 3%