Impact of combinations of antineoplastic drugs on intestinal microflora in 9 patients with leukaemia.

Anna Nyhlén; Bengt Ljungberg; Ingrid Nilsson-Ehle; Carl Erik Nord

doi:10.1080/00365540110076994

Impact of combinations of antineoplastic drugs on intestinal microflora in 9 patients with leukaemia.

Anna Nyhlén, Bengt Ljungberg, Ingrid Nilsson-Ehle, Carl Erik Nord

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Abstract

The impact of antineoplastic drugs on the intestinal microflora was studied in 9 patients with acute leukaemia during chemotherapy and in 5 patients also during chemotherapy-induced neutropenia. Quantitative and qualitative microbiological analyses of faecal samples obtained before and during chemotherapy showed significantly increased counts of Bacteroides spp. in 3/9 patients and, during neutropenia, significantly increased counts of yeasts in 2/5 patients; however, the intestinal microflora was stable in most patients.

Original language	English
Pages (from-to)	17-21
Journal	Scandinavian Journal of Infectious Diseases
Volume	34
Issue number	1
DOIs	https://doi.org/10.1080/00365540110076994
Publication status	Published - 2002

Subject classification (UKÄ)

Infectious Medicine

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10.1080/00365540110076994

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title = "Impact of combinations of antineoplastic drugs on intestinal microflora in 9 patients with leukaemia.",

abstract = "The impact of antineoplastic drugs on the intestinal microflora was studied in 9 patients with acute leukaemia during chemotherapy and in 5 patients also during chemotherapy-induced neutropenia. Quantitative and qualitative microbiological analyses of faecal samples obtained before and during chemotherapy showed significantly increased counts of Bacteroides spp. in 3/9 patients and, during neutropenia, significantly increased counts of yeasts in 2/5 patients; however, the intestinal microflora was stable in most patients.",

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AU - Nilsson-Ehle, Ingrid

AU - Nord, Carl Erik

PY - 2002

Y1 - 2002

N2 - The impact of antineoplastic drugs on the intestinal microflora was studied in 9 patients with acute leukaemia during chemotherapy and in 5 patients also during chemotherapy-induced neutropenia. Quantitative and qualitative microbiological analyses of faecal samples obtained before and during chemotherapy showed significantly increased counts of Bacteroides spp. in 3/9 patients and, during neutropenia, significantly increased counts of yeasts in 2/5 patients; however, the intestinal microflora was stable in most patients.

AB - The impact of antineoplastic drugs on the intestinal microflora was studied in 9 patients with acute leukaemia during chemotherapy and in 5 patients also during chemotherapy-induced neutropenia. Quantitative and qualitative microbiological analyses of faecal samples obtained before and during chemotherapy showed significantly increased counts of Bacteroides spp. in 3/9 patients and, during neutropenia, significantly increased counts of yeasts in 2/5 patients; however, the intestinal microflora was stable in most patients.

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DO - 10.1080/00365540110076994

M3 - Article

SN - 1651-1980

VL - 34

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JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 1

ER -

Impact of combinations of antineoplastic drugs on intestinal microflora in 9 patients with leukaemia.

Abstract

Subject classification (UKÄ)

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