Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

Andreas Edsfeldt; Isabel Goncalves; Helena Grufman; Mihaela Nitulescu; Pontus Dunér; Eva Bengtsson; Ines Mollet; Ana Persson; Marie MN Nilsson; Marju Orho-Melander; Olle Melander; Harry Björkbacka; Jan Nilsson

doi:10.1161/ATVBAHA.114.303414

Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

Andreas Edsfeldt, Isabel Goncalves, Helena Grufman, Mihaela Nitulescu, Pontus Dunér, Eva Bengtsson, Ines Mollet, Ana Persson, Marie MN Nilsson, Marju Orho-Melander, Olle Melander, Harry Björkbacka, Jan Nilsson

Research output: Contribution to journal › Article › peer-review

Abstract

Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.

Original language	English
Pages (from-to)	2143-2150
Journal	Arteriosclerosis, Thrombosis and Vascular Biology
Volume	34
Issue number	9
DOIs	https://doi.org/10.1161/ATVBAHA.114.303414
Publication status	Published - 2014

Subject classification (UKÄ)

Cardiac and Cardiovascular Systems

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1161/ATVBAHA.114.303414

http://www.ncbi.nlm.nih.gov/pubmed/25035341?dopt=Abstract

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Edsfeldt, A., Goncalves, I., Grufman, H., Nitulescu, M., Dunér, P., Bengtsson, E., Mollet, I., Persson, A., Nilsson, M. MN., Orho-Melander, M., Melander, O., Björkbacka, H., & Nilsson, J. (2014). Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes. Arteriosclerosis, Thrombosis and Vascular Biology, 34(9), 2143-2150. https://doi.org/10.1161/ATVBAHA.114.303414

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title = "Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.",

abstract = "Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.",

author = "Andreas Edsfeldt and Isabel Goncalves and Helena Grufman and Mihaela Nitulescu and Pontus Dun{\'e}r and Eva Bengtsson and Ines Mollet and Ana Persson and Nilsson, {Marie MN} and Marju Orho-Melander and Olle Melander and Harry Bj{\"o}rkbacka and Jan Nilsson",

year = "2014",

doi = "10.1161/ATVBAHA.114.303414",

language = "English",

volume = "34",

pages = "2143--2150",

journal = "Arteriosclerosis, Thrombosis and Vascular Biology",

issn = "1524-4636",

publisher = "Lippincott Williams & Wilkins",

number = "9",

}

Edsfeldt, A , Goncalves, I, Grufman, H, Nitulescu, M , Dunér, P , Bengtsson, E, Mollet, I, Persson, A, Nilsson, MMN, Orho-Melander, M , Melander, O , Björkbacka, H & Nilsson, J 2014, 'Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 34, no. 9, pp. 2143-2150. https://doi.org/10.1161/ATVBAHA.114.303414

TY - JOUR

T1 - Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

AU - Edsfeldt, Andreas

AU - Goncalves, Isabel

AU - Grufman, Helena

AU - Nitulescu, Mihaela

AU - Dunér, Pontus

AU - Bengtsson, Eva

AU - Mollet, Ines

AU - Persson, Ana

AU - Nilsson, Marie MN

AU - Orho-Melander, Marju

AU - Melander, Olle

AU - Björkbacka, Harry

AU - Nilsson, Jan

PY - 2014

Y1 - 2014

N2 - Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.

AB - Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.

U2 - 10.1161/ATVBAHA.114.303414

DO - 10.1161/ATVBAHA.114.303414

M3 - Article

C2 - 25035341

SN - 1524-4636

VL - 34

SP - 2143

EP - 2150

JO - Arteriosclerosis, Thrombosis and Vascular Biology

JF - Arteriosclerosis, Thrombosis and Vascular Biology

IS - 9

ER -

Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

Abstract

Subject classification (UKÄ)

UN SDGs

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