Abstract
We present an improved acoustophoretic system for circulating tumor cell separation from blood. The system is operated by pressure driven flow, including flow sensors and a feed-back loop for precise flow control. The pressure driven system provides a user interface that can be handled by a non-skilled operator, and most importantly full clinical samples of 7 mL can be processed in 70 minutes. The improved flow control enables recovery of rare tumor cell populations ≈10 cells/mL spiked in whole blood at a recovery close to 100%.
Original language | English |
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Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 594-596 |
ISBN (Electronic) | 9780979806476 |
Publication status | Published - 2014 |
Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: 2014 Oct 26 → 2014 Oct 30 Conference number: 18 |
Publication series
Name | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
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Conference
Conference | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
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Country/Territory | United States |
City | San Antonio |
Period | 2014/10/26 → 2014/10/30 |
Bibliographical note
Publisher Copyright:© 14CBMS.
Subject classification (UKÄ)
- Medical Biotechnology
Free keywords
- Acoustophoresis
- Cancer
- Circulation tumor cells
- Rare cell
- Separation