Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Daniel Söderberg, Tino Kurz, Atbin Motamedi, Thomas Hellmark, Per Eriksson, Mårten Segelmark

Research output: Contribution to journalArticlepeer-review

Abstract

Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.
Original languageEnglish
Pages (from-to)2085-2094
JournalRheumatology
Volume54
Issue number11
DOIs
Publication statusPublished - 2015

Subject classification (UKÄ)

  • Clinical Medicine

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