Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Daniel Söderberg; Tino Kurz; Atbin Motamedi; Thomas Hellmark; Per Eriksson; Mårten Segelmark

doi:10.1093/rheumatology/kev217

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Daniel Söderberg, Tino Kurz, Atbin Motamedi, Thomas Hellmark, Per Eriksson, Mårten Segelmark

Research output: Contribution to journal › Article › peer-review

Abstract

Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.

Original language	English
Pages (from-to)	2085-2094
Journal	Rheumatology
Volume	54
Issue number	11
DOIs	https://doi.org/10.1093/rheumatology/kev217
Publication status	Published - 2015

Subject classification (UKÄ)

Clinical Medicine

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10.1093/rheumatology/kev217

http://www.ncbi.nlm.nih.gov/pubmed/26170375?dopt=Abstract

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Söderberg, D., Kurz, T., Motamedi, A., Hellmark, T., Eriksson, P., & Segelmark, M. (2015). Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. Rheumatology, 54(11), 2085-2094. https://doi.org/10.1093/rheumatology/kev217

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title = "Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.",

abstract = "Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.",

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Söderberg, D, Kurz, T, Motamedi, A, Hellmark, T, Eriksson, P & Segelmark, M 2015, 'Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.', Rheumatology, vol. 54, no. 11, pp. 2085-2094. https://doi.org/10.1093/rheumatology/kev217

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. / Söderberg, Daniel; Kurz, Tino; Motamedi, Atbin et al.
In: Rheumatology, Vol. 54, No. 11, 2015, p. 2085-2094.

Research output: Contribution to journal › Article › peer-review

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AU - Söderberg, Daniel

AU - Kurz, Tino

AU - Motamedi, Atbin

AU - Hellmark, Thomas

AU - Eriksson, Per

AU - Segelmark, Mårten

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