Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Daniel Söderberg; Tino Kurz; Atbin Motamedi; Thomas Hellmark; Per Eriksson; Mårten Segelmark

doi:10.1093/rheumatology/kev217

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Daniel Söderberg, Tino Kurz, Atbin Motamedi, Thomas Hellmark, Per Eriksson, Mårten Segelmark

Research output: Contribution to journal › Article › peer-review

Abstract

Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.

Original language	English
Pages (from-to)	2085-2094
Journal	Rheumatology
Volume	54
Issue number	11
DOIs	https://doi.org/10.1093/rheumatology/kev217
Publication status	Published - 2015

Subject classification (UKÄ)

Clinical Medicine

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10.1093/rheumatology/kev217

http://www.ncbi.nlm.nih.gov/pubmed/26170375?dopt=Abstract

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Söderberg, D., Kurz, T., Motamedi, A., Hellmark, T., Eriksson, P., & Segelmark, M. (2015). Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. Rheumatology, 54(11), 2085-2094. https://doi.org/10.1093/rheumatology/kev217

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title = "Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.",

abstract = "Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.",

author = "Daniel S{\"o}derberg and Tino Kurz and Atbin Motamedi and Thomas Hellmark and Per Eriksson and M{\aa}rten Segelmark",

year = "2015",

doi = "10.1093/rheumatology/kev217",

language = "English",

volume = "54",

pages = "2085--2094",

journal = "Rheumatology",

issn = "1462-0332",

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Söderberg, D, Kurz, T, Motamedi, A, Hellmark, T, Eriksson, P & Segelmark, M 2015, 'Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.', Rheumatology, vol. 54, no. 11, pp. 2085-2094. https://doi.org/10.1093/rheumatology/kev217

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission. / Söderberg, Daniel; Kurz, Tino; Motamedi, Atbin et al.
In: Rheumatology, Vol. 54, No. 11, 2015, p. 2085-2094.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

AU - Söderberg, Daniel

AU - Kurz, Tino

AU - Motamedi, Atbin

AU - Hellmark, Thomas

AU - Eriksson, Per

AU - Segelmark, Mårten

PY - 2015

Y1 - 2015

N2 - Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.

AB - Neutrophil extracellular traps (NETs) have been visualized at the site of ANCA-associated vasculitis (AAV) lesions. Increased levels of NET remnants in the circulation have been reported in some AAV patients with active disease. The aim of the present study was to analyse NET remnants in a larger cohort of AAV patients with varying degrees of disease activity and to elucidate possible factors responsible for remnant variation.

UR - https://www.scopus.com/pages/publications/84946712446

U2 - 10.1093/rheumatology/kev217

DO - 10.1093/rheumatology/kev217

M3 - Article

C2 - 26170375

SN - 1462-0332

VL - 54

SP - 2085

EP - 2094

JO - Rheumatology

JF - Rheumatology

IS - 11

ER -

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Abstract

Subject classification (UKÄ)

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